Cargando…

The Development, Fine Specificity, and Importance of High-Avidity Antibodies to VAR2CSA in Pregnant Cameroonian Women Living in Yaoundé, an Urban City

Pregnant women infected with Plasmodium falciparum often produce antibodies (Abs) to VAR2CSA, a ligand that binds to placental chondroitin sulfate A causing placental malaria (PM). Antibodies to VAR2CSA are associated with improved pregnancy outcomes. Antibody avidity is a surrogate marker for the e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vanda, Koko, Bobbili, Naveen, Matsunaga, Masako, Chen, John J., Salanti, Ali, Leke, Rose F. G., Taylor, Diane Wallace
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953046/ https://www.ncbi.nlm.nih.gov/pubmed/33717094 http://dx.doi.org/10.3389/fimmu.2021.610108

Ejemplares similares

The Antibody Response of Pregnant Cameroonian Women to VAR2CSA ID1-ID2a, a Small Recombinant Protein Containing the CSA-Binding Site
por: Babakhanyan, Anna, et al.
Publicado: (2014)

High Avidity Antibodies to Full-Length VAR2CSA Correlate with Absence of Placental Malaria
por: Tutterrow, Yeung Lo, et al.
Publicado: (2012)

Comparison of the specificity of antibodies to VAR2CSA in Cameroonian multigravidae with and without placental malaria: a retrospective case–control study
por: Babakhanyan, Anna, et al.
Publicado: (2015)

Antibody responses to the full-length VAR2CSA and its DBL domains in Cameroonian children and teenagers
por: Fodjo, Barriere A. Y., et al.
Publicado: (2016)

Antibodies to full-length and the DBL5 domain of VAR2CSA in pregnant women after long-term implementation of intermittent preventive treatment in Etoudi, Cameroon
por: Djontu, Jean Claude, et al.
Publicado: (2020)

Measuring antibody avidity to Plasmodium falciparum merozoite antigens using a multiplex immunoassay approach
por: Taylor, Diane Wallace, et al.
Publicado: (2020)

Structure function analysis of P. falciparum VAR2CSA
por: Dahlbäck, Madeleine, et al.
Publicado: (2010)

Evidence for the Involvement of VAR2CSA in Pregnancy-associated Malaria
por: Salanti, Ali, et al.
Publicado: (2004)

Differential evolution of anti-VAR2CSA- IgG3 in primigravidae and multigravidae pregnant women infected by Plasmodium falciparum
por: Guitard, Juliette, et al.
Publicado: (2008)

Structural Insight into Epitopes in the Pregnancy-Associated Malaria Protein VAR2CSA
por: Andersen, Pernille, et al.
Publicado: (2008)

Utilizing Nanobody Technology to Target Non-Immunodominant Domains of VAR2CSA
por: Ditlev, Sisse B., et al.
Publicado: (2014)

Statistical prediction of immunity to placental malaria based on multi-assay antibody data for malarial antigens
por: Siriwardhana, Chathura, et al.
Publicado: (2017)

Arterial compliance in a group of normotensive and untreated hypertensive Cameroonian subjects in Yaounde
por: Kingue, Samuel, et al.
Publicado: (2016)

An Upstream Open Reading Frame Controls Translation of var2csa, a Gene Implicated in Placental Malaria
por: Amulic, Borko, et al.
Publicado: (2009)

Var2CSA Minimal CSA Binding Region Is Located within the N-Terminal Region
por: Srivastava, Anand, et al.
Publicado: (2011)

Internalization and trafficking of CSPG-bound recombinant VAR2CSA lectins in cancer cells
por: Wang, Chris Kedong, et al.
Publicado: (2022)

Identification and Characterization of B-Cell Epitopes in the DBL4ε Domain of VAR2CSA
por: Ditlev, Sisse B., et al.
Publicado: (2012)

Identification of glycosaminoglycan binding regions in the Plasmodium falciparum encoded placental sequestration ligand, VAR2CSA
por: Resende, Mafalda, et al.
Publicado: (2008)

Several domains from VAR2CSA can induce Plasmodium falciparum adhesion-blocking antibodies
por: Salanti, Ali, et al.
Publicado: (2010)

Phosphorylation of the VAR2CSA extracellular region is associated with enhanced adhesive properties to the placental receptor CSA
por: Dorin-Semblat, Dominique, et al.
Publicado: (2019)

Identification of a Major Dimorphic Region in the Functionally Critical N-Terminal ID1 Domain of VAR2CSA
por: Doritchamou, Justin, et al.
Publicado: (2015)

The Chondroitin Sulfate A-binding Site of the VAR2CSA Protein Involves Multiple N-terminal Domains
por: Dahlbäck, Madeleine, et al.
Publicado: (2011)

A Novel Virus-Like Particle Based Vaccine Platform Displaying the Placental Malaria Antigen VAR2CSA
por: Thrane, Susan, et al.
Publicado: (2015)

Capture and Detection of Circulating Glioma Cells Using the Recombinant VAR2CSA Malaria Protein
por: Bang-Christensen, Sara R., et al.
Publicado: (2019)

Individuals living in a malaria-endemic area of Cameroon do not have an acquired antibody response to Plasmodium falciparum histidine-rich protein 2
por: Taylor, Diane Wallace, et al.
Publicado: (2017)

Differential Induction of Functional IgG Using the Plasmodium falciparum Placental Malaria Vaccine Candidate VAR2CSA
por: Pinto, Vera V., et al.
Publicado: (2011)

Human pregnancy-associated malaria-specific B cells target polymorphic, conformational epitopes in VAR2CSA
por: Barfod, Lea, et al.
Publicado: (2007)

Detection of VAR2CSA-Captured Colorectal Cancer Cells from Blood Samples by Real-Time Reverse Transcription PCR
por: Bang-Christensen, Sara R., et al.
Publicado: (2021)

Epitope Mapping and Topographic Analysis of VAR2CSA DBL3X Involved in P. falciparum Placental Sequestration
por: Dahlbäck, Madeleine, et al.
Publicado: (2006)

VAR2CSA Signatures of High Plasmodium falciparum Parasitemia in the Placenta
por: Rovira-Vallbona, Eduard, et al.
Publicado: (2013)

The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner
por: Agerbæk, Mette Ø., et al.
Publicado: (2018)

Infections with Plasmodium falciparum during pregnancy affect VAR2CSA DBL-5 domain-specific T cell cytokine responses
por: Gbédandé, Komi, et al.
Publicado: (2016)

High Antibodies to VAR2CSA in Response to Malaria Infection Are Associated With Improved Birthweight in a Longitudinal Study of Pregnant Women
por: McLean, Alistair R. D., et al.
Publicado: (2021)

Multiple var2csa-Type PfEMP1 Genes Located at Different Chromosomal Loci Occur in Many Plasmodium falciparum Isolates
por: Sander, Adam F., et al.
Publicado: (2009)

Full-Length Recombinant Plasmodium falciparum VAR2CSA Binds Specifically to CSPG and Induces Potent Parasite Adhesion-Blocking Antibodies
por: Khunrae, Pongsak, et al.
Publicado: (2010)

Default Pathway of var2csa Switching and Translational Repression in Plasmodium falciparum
por: Mok, Bobo W., et al.
Publicado: (2008)

Designing a VAR2CSA-based vaccine to prevent placental malaria()
por: Fried, Michal, et al.
Publicado: (2015)

Plasmodium falciparum genetic variation of var2csa in the Democratic Republic of the Congo
por: Verity, Robert, et al.
Publicado: (2018)

VAR2CSA Serology to Detect Plasmodium falciparum Transmission Patterns in Pregnancy
por: Fonseca, Ana Maria, et al.
Publicado: (2019)

Structural basis for placental malaria mediated by Plasmodium falciparum VAR2CSA
por: Ma, Rui, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_tagin3kdfir50mkci4hshvus71