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Single-Stage Arthroscopic Cartilage Repair With Injectable Scaffold and BMAC

Injectable scaffold augmentation is a promising modality for single-stage cartilage repair. According to published studies, cartilage repair with scaffold augmentation has improved clinical outcomes, radiological fill, and histological repair compared with microfracture alone. Injectable scaffolds h...

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Detalles Bibliográficos
Autores principales: Heng, Christian Hwee Yee, Snow, Martyn, Dave, Lee Yee Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953231/
https://www.ncbi.nlm.nih.gov/pubmed/33738211
http://dx.doi.org/10.1016/j.eats.2020.10.065
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author Heng, Christian Hwee Yee
Snow, Martyn
Dave, Lee Yee Han
author_facet Heng, Christian Hwee Yee
Snow, Martyn
Dave, Lee Yee Han
author_sort Heng, Christian Hwee Yee
collection PubMed
description Injectable scaffold augmentation is a promising modality for single-stage cartilage repair. According to published studies, cartilage repair with scaffold augmentation has improved clinical outcomes, radiological fill, and histological repair compared with microfracture alone. Injectable scaffolds have the versatility to be used in large and irregularly shaped lesions. With correct preparation, they can be applied to lesions on the femoral condyle that may be vertical, or even inverted lesions such as those in the patella. They can be combined with bone marrow aspirate concentrate (BMAC) to provide mesenchymal stem cells (MSCs), thereby avoiding the need for microfracture. This protects the subchondral plate, preventing biomechanical alteration and potentially resulting in improved long-term outcomes. In this article, we demonstrate the utility of injectable scaffolds and their combination with BMAC.
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spelling pubmed-79532312021-03-17 Single-Stage Arthroscopic Cartilage Repair With Injectable Scaffold and BMAC Heng, Christian Hwee Yee Snow, Martyn Dave, Lee Yee Han Arthrosc Tech Technical Note Injectable scaffold augmentation is a promising modality for single-stage cartilage repair. According to published studies, cartilage repair with scaffold augmentation has improved clinical outcomes, radiological fill, and histological repair compared with microfracture alone. Injectable scaffolds have the versatility to be used in large and irregularly shaped lesions. With correct preparation, they can be applied to lesions on the femoral condyle that may be vertical, or even inverted lesions such as those in the patella. They can be combined with bone marrow aspirate concentrate (BMAC) to provide mesenchymal stem cells (MSCs), thereby avoiding the need for microfracture. This protects the subchondral plate, preventing biomechanical alteration and potentially resulting in improved long-term outcomes. In this article, we demonstrate the utility of injectable scaffolds and their combination with BMAC. Elsevier 2021-02-08 /pmc/articles/PMC7953231/ /pubmed/33738211 http://dx.doi.org/10.1016/j.eats.2020.10.065 Text en © 2020 by the Arthroscopy Association of North America. Published by Elsevier. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Technical Note
Heng, Christian Hwee Yee
Snow, Martyn
Dave, Lee Yee Han
Single-Stage Arthroscopic Cartilage Repair With Injectable Scaffold and BMAC
title Single-Stage Arthroscopic Cartilage Repair With Injectable Scaffold and BMAC
title_full Single-Stage Arthroscopic Cartilage Repair With Injectable Scaffold and BMAC
title_fullStr Single-Stage Arthroscopic Cartilage Repair With Injectable Scaffold and BMAC
title_full_unstemmed Single-Stage Arthroscopic Cartilage Repair With Injectable Scaffold and BMAC
title_short Single-Stage Arthroscopic Cartilage Repair With Injectable Scaffold and BMAC
title_sort single-stage arthroscopic cartilage repair with injectable scaffold and bmac
topic Technical Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953231/
https://www.ncbi.nlm.nih.gov/pubmed/33738211
http://dx.doi.org/10.1016/j.eats.2020.10.065
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