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Single-Stage Arthroscopic Cartilage Repair With Injectable Scaffold and BMAC
Injectable scaffold augmentation is a promising modality for single-stage cartilage repair. According to published studies, cartilage repair with scaffold augmentation has improved clinical outcomes, radiological fill, and histological repair compared with microfracture alone. Injectable scaffolds h...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953231/ https://www.ncbi.nlm.nih.gov/pubmed/33738211 http://dx.doi.org/10.1016/j.eats.2020.10.065 |
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author | Heng, Christian Hwee Yee Snow, Martyn Dave, Lee Yee Han |
author_facet | Heng, Christian Hwee Yee Snow, Martyn Dave, Lee Yee Han |
author_sort | Heng, Christian Hwee Yee |
collection | PubMed |
description | Injectable scaffold augmentation is a promising modality for single-stage cartilage repair. According to published studies, cartilage repair with scaffold augmentation has improved clinical outcomes, radiological fill, and histological repair compared with microfracture alone. Injectable scaffolds have the versatility to be used in large and irregularly shaped lesions. With correct preparation, they can be applied to lesions on the femoral condyle that may be vertical, or even inverted lesions such as those in the patella. They can be combined with bone marrow aspirate concentrate (BMAC) to provide mesenchymal stem cells (MSCs), thereby avoiding the need for microfracture. This protects the subchondral plate, preventing biomechanical alteration and potentially resulting in improved long-term outcomes. In this article, we demonstrate the utility of injectable scaffolds and their combination with BMAC. |
format | Online Article Text |
id | pubmed-7953231 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-79532312021-03-17 Single-Stage Arthroscopic Cartilage Repair With Injectable Scaffold and BMAC Heng, Christian Hwee Yee Snow, Martyn Dave, Lee Yee Han Arthrosc Tech Technical Note Injectable scaffold augmentation is a promising modality for single-stage cartilage repair. According to published studies, cartilage repair with scaffold augmentation has improved clinical outcomes, radiological fill, and histological repair compared with microfracture alone. Injectable scaffolds have the versatility to be used in large and irregularly shaped lesions. With correct preparation, they can be applied to lesions on the femoral condyle that may be vertical, or even inverted lesions such as those in the patella. They can be combined with bone marrow aspirate concentrate (BMAC) to provide mesenchymal stem cells (MSCs), thereby avoiding the need for microfracture. This protects the subchondral plate, preventing biomechanical alteration and potentially resulting in improved long-term outcomes. In this article, we demonstrate the utility of injectable scaffolds and their combination with BMAC. Elsevier 2021-02-08 /pmc/articles/PMC7953231/ /pubmed/33738211 http://dx.doi.org/10.1016/j.eats.2020.10.065 Text en © 2020 by the Arthroscopy Association of North America. Published by Elsevier. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Technical Note Heng, Christian Hwee Yee Snow, Martyn Dave, Lee Yee Han Single-Stage Arthroscopic Cartilage Repair With Injectable Scaffold and BMAC |
title | Single-Stage Arthroscopic Cartilage Repair With Injectable Scaffold and BMAC |
title_full | Single-Stage Arthroscopic Cartilage Repair With Injectable Scaffold and BMAC |
title_fullStr | Single-Stage Arthroscopic Cartilage Repair With Injectable Scaffold and BMAC |
title_full_unstemmed | Single-Stage Arthroscopic Cartilage Repair With Injectable Scaffold and BMAC |
title_short | Single-Stage Arthroscopic Cartilage Repair With Injectable Scaffold and BMAC |
title_sort | single-stage arthroscopic cartilage repair with injectable scaffold and bmac |
topic | Technical Note |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953231/ https://www.ncbi.nlm.nih.gov/pubmed/33738211 http://dx.doi.org/10.1016/j.eats.2020.10.065 |
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