Endoplasmic reticulum maintains ion homeostasis required for plasma membrane repair

Of the many crucial functions of the ER, homeostasis of physiological calcium increase is critical for signaling. Plasma membrane (PM) injury causes a pathological calcium influx. Here, we show that the ER helps clear this surge in cytoplasmic calcium through an ER-resident calcium pump, SERCA, and...

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Detalles Bibliográficos
Autores principales: Chandra, Goutam, Sreetama, Sen Chandra, Mázala, Davi A.G., Charton, Karine, VanderMeulen, Jack H., Richard, Isabelle, Jaiswal, Jyoti K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953257/
https://www.ncbi.nlm.nih.gov/pubmed/33688936
http://dx.doi.org/10.1083/jcb.202006035

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