Hepatic Gadd45β promotes hyperglycemia and glucose intolerance through DNA demethylation of PGC-1α

Although widely used for their potent anti-inflammatory and immunosuppressive properties, the prescription of glucocorticoid analogues (e.g., dexamethasone) has been associated with deleterious glucose metabolism, compromising their long-term therapeutic use. However, the molecular mechanism remains...

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Detalles Bibliográficos
Autores principales: Wu, Ling, Jiao, Yang, Li, Yao, Jiang, Jingjing, Zhao, Lin, Li, Menghui, Li, Bin, Yan, Zheng, Chen, Xuejin, Li, Xiaoying, Lu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953268/
https://www.ncbi.nlm.nih.gov/pubmed/33688917
http://dx.doi.org/10.1084/jem.20201475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953268/
https://www.ncbi.nlm.nih.gov/pubmed/33688917
http://dx.doi.org/10.1084/jem.20201475

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