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Open reduction and internal fixation (ORIF) versus ORIF and primary subtalar arthrodesis for complex displaced intraarticular calcaneus fractures: An expected value decision analysis

OBJECTIVES: To determine the optimal patient-oriented treatment between open reduction and internal fixation (ORIF) with or without primary subtalar arthrodesis (PSTA) for patients with displaced intraarticular calcaneus fractures (DIACFs, OTA 82-C3 and C4). DESIGN: Expected value decision analysis....

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Autores principales: Eisenstein, Emmanuel David, Kusnezov, Nicholas A., Waterman, Brian R., Orr, Justin D., Blair, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953466/
https://www.ncbi.nlm.nih.gov/pubmed/33937643
http://dx.doi.org/10.1097/OI9.0000000000000005
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author Eisenstein, Emmanuel David
Kusnezov, Nicholas A.
Waterman, Brian R.
Orr, Justin D.
Blair, James A.
author_facet Eisenstein, Emmanuel David
Kusnezov, Nicholas A.
Waterman, Brian R.
Orr, Justin D.
Blair, James A.
author_sort Eisenstein, Emmanuel David
collection PubMed
description OBJECTIVES: To determine the optimal patient-oriented treatment between open reduction and internal fixation (ORIF) with or without primary subtalar arthrodesis (PSTA) for patients with displaced intraarticular calcaneus fractures (DIACFs, OTA 82-C3 and C4). DESIGN: Expected value decision analysis. SETTING: Academic military treatment facility PARTICIPANTS: One hundred randomly selected volunteers. INTERVENTION: Hypothetical clinical scenario involving ORIF versus ORIF with PSTA. MAIN OUTCOME MEASUREMENTS: Decision analysis was used to elucidate the superior treatment option based on expected patient values, composed of: the product of the average outcome probabilities established by previously published studies and the average ascribed patient utility values for each outcome probability. One-way sensitivity analysis was performed to quantify the amount of change required for the inferior treatment to equal or surpass the superior option. RESULTS: Expected values for ORIF and ORIF with PSTA were 8.96 and 18.06, respectively, favoring ORIF with PSTA. One-way sensitivity analysis was performed by artificially decreasing the rate of secondary fusion following isolated ORIF thus increasing its overall expected value. Adjusting the rate of secondary fusion to 0%, the expected value of ORIF with PSTA nearly doubled that of ORIF (18.06 vs 9.45). Similarly, when adjusting the moderate and severe complication rates following ORIF with PSTA to 100%, the expected value of ORIF with PSTA still exceeded that of ORIF (15.45 vs 8.96, and 13.52 vs 8.96, respectively). CONCLUSION: Expected value decision analysis favors ORIF with PSTA as the optimal treatment for complex DIACF.
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spelling pubmed-79534662021-04-29 Open reduction and internal fixation (ORIF) versus ORIF and primary subtalar arthrodesis for complex displaced intraarticular calcaneus fractures: An expected value decision analysis Eisenstein, Emmanuel David Kusnezov, Nicholas A. Waterman, Brian R. Orr, Justin D. Blair, James A. OTA Int OTA Funding Award Winner OBJECTIVES: To determine the optimal patient-oriented treatment between open reduction and internal fixation (ORIF) with or without primary subtalar arthrodesis (PSTA) for patients with displaced intraarticular calcaneus fractures (DIACFs, OTA 82-C3 and C4). DESIGN: Expected value decision analysis. SETTING: Academic military treatment facility PARTICIPANTS: One hundred randomly selected volunteers. INTERVENTION: Hypothetical clinical scenario involving ORIF versus ORIF with PSTA. MAIN OUTCOME MEASUREMENTS: Decision analysis was used to elucidate the superior treatment option based on expected patient values, composed of: the product of the average outcome probabilities established by previously published studies and the average ascribed patient utility values for each outcome probability. One-way sensitivity analysis was performed to quantify the amount of change required for the inferior treatment to equal or surpass the superior option. RESULTS: Expected values for ORIF and ORIF with PSTA were 8.96 and 18.06, respectively, favoring ORIF with PSTA. One-way sensitivity analysis was performed by artificially decreasing the rate of secondary fusion following isolated ORIF thus increasing its overall expected value. Adjusting the rate of secondary fusion to 0%, the expected value of ORIF with PSTA nearly doubled that of ORIF (18.06 vs 9.45). Similarly, when adjusting the moderate and severe complication rates following ORIF with PSTA to 100%, the expected value of ORIF with PSTA still exceeded that of ORIF (15.45 vs 8.96, and 13.52 vs 8.96, respectively). CONCLUSION: Expected value decision analysis favors ORIF with PSTA as the optimal treatment for complex DIACF. Wolters Kluwer Health 2020-09-13 /pmc/articles/PMC7953466/ /pubmed/33937643 http://dx.doi.org/10.1097/OI9.0000000000000005 Text en Copyright © 2018 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of the Orthopaedic Trauma Association. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0
spellingShingle OTA Funding Award Winner
Eisenstein, Emmanuel David
Kusnezov, Nicholas A.
Waterman, Brian R.
Orr, Justin D.
Blair, James A.
Open reduction and internal fixation (ORIF) versus ORIF and primary subtalar arthrodesis for complex displaced intraarticular calcaneus fractures: An expected value decision analysis
title Open reduction and internal fixation (ORIF) versus ORIF and primary subtalar arthrodesis for complex displaced intraarticular calcaneus fractures: An expected value decision analysis
title_full Open reduction and internal fixation (ORIF) versus ORIF and primary subtalar arthrodesis for complex displaced intraarticular calcaneus fractures: An expected value decision analysis
title_fullStr Open reduction and internal fixation (ORIF) versus ORIF and primary subtalar arthrodesis for complex displaced intraarticular calcaneus fractures: An expected value decision analysis
title_full_unstemmed Open reduction and internal fixation (ORIF) versus ORIF and primary subtalar arthrodesis for complex displaced intraarticular calcaneus fractures: An expected value decision analysis
title_short Open reduction and internal fixation (ORIF) versus ORIF and primary subtalar arthrodesis for complex displaced intraarticular calcaneus fractures: An expected value decision analysis
title_sort open reduction and internal fixation (orif) versus orif and primary subtalar arthrodesis for complex displaced intraarticular calcaneus fractures: an expected value decision analysis
topic OTA Funding Award Winner
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953466/
https://www.ncbi.nlm.nih.gov/pubmed/33937643
http://dx.doi.org/10.1097/OI9.0000000000000005
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