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Tanshinone IIA induces ferroptosis in gastric cancer cells through p53-mediated SLC7A11 down-regulation

Gastric cancer represents a malignant type of cancer worldwide. Tanshinone IIA (Tan IIA), a pharmacologically active component isolated from the rhizome of the Chinese herb Salvia miltiorrhiza Bunge (Danshen), has been reported to possess an anti-cancer effect in gastric cancer. However, its mechani...

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Detalles Bibliográficos
Autores principales: Guan, Zhenhua, Chen, Jing, Li, Xueliang, Dong, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953492/
https://www.ncbi.nlm.nih.gov/pubmed/32776119
http://dx.doi.org/10.1042/BSR20201807