Dissecting the Role of BET Bromodomain Proteins BRD2 and BRD4 in Human NK Cell Function

Natural killer (NK) cells are innate lymphocytes that play a pivotal role in the immune surveillance and elimination of transformed or virally infected cells. Using a chemo-genetic approach, we identify BET bromodomain containing proteins BRD2 and BRD4 as central regulators of NK cell functions, inc...

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Detalles Bibliográficos
Autores principales: Cribbs, Adam P., Filippakopoulos, Panagis, Philpott, Martin, Wells, Graham, Penn, Henry, Oerum, Henrik, Valge-Archer, Viia, Feldmann, Marc, Oppermann, Udo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953504/
https://www.ncbi.nlm.nih.gov/pubmed/33717143
http://dx.doi.org/10.3389/fimmu.2021.626255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953504/
https://www.ncbi.nlm.nih.gov/pubmed/33717143
http://dx.doi.org/10.3389/fimmu.2021.626255

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