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Prevalence of childhood Cancer among children attending referral hospitals of outpatient Department in Ethiopia

INTRODUCTION: Childhood cancer is one of the leading causes of morbidity and mortality in the pediatrics age group. The problem affects both developed and developing countries. A high mortality rate has been observed in low-income counties. Despite its high fatality rate, less attention has been pai...

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Autores principales: Endalamaw, Aklilu, Assimamaw, Nega Tezera, Ayele, Tadesse Awoke, Muche, Achenef Asmamaw, Zeleke, Ejigu Gebeye, Wondim, Amare, Belay, Getaneh Mulualem, Birhanu, Yeneabat, Tazebew, Ashenafi, Techane, Masresha Asmare, Kassa, Selam Fisha, Wubneh, Chalachew Adugna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953643/
https://www.ncbi.nlm.nih.gov/pubmed/33711955
http://dx.doi.org/10.1186/s12885-021-08014-0
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author Endalamaw, Aklilu
Assimamaw, Nega Tezera
Ayele, Tadesse Awoke
Muche, Achenef Asmamaw
Zeleke, Ejigu Gebeye
Wondim, Amare
Belay, Getaneh Mulualem
Birhanu, Yeneabat
Tazebew, Ashenafi
Techane, Masresha Asmare
Kassa, Selam Fisha
Wubneh, Chalachew Adugna
author_facet Endalamaw, Aklilu
Assimamaw, Nega Tezera
Ayele, Tadesse Awoke
Muche, Achenef Asmamaw
Zeleke, Ejigu Gebeye
Wondim, Amare
Belay, Getaneh Mulualem
Birhanu, Yeneabat
Tazebew, Ashenafi
Techane, Masresha Asmare
Kassa, Selam Fisha
Wubneh, Chalachew Adugna
author_sort Endalamaw, Aklilu
collection PubMed
description INTRODUCTION: Childhood cancer is one of the leading causes of morbidity and mortality in the pediatrics age group. The problem affects both developed and developing countries. A high mortality rate has been observed in low-income counties. Despite its high fatality rate, less attention has been paid to the problem in developing countries, including Ethiopia. For this reason, childhood cancer is not well documented in the study setting. Therefore, we assessed the prevalence of childhood cancer in Ethiopia. METHODS: Institution based cross-sectional study design from January 1, 2019, to March 30, 2019, was conducted in the pediatrics treatment center. A systematic random sampling technique has used to select 1270 children in the pediatric outpatient department. The data were entered using Epi info version 7 and exported to SPSS version 20 for analysis. We checked model fitness for the advanced statistical methods, but it was difficult to proceed with logistic regression model to see the association between dependent and explanatory variables because of the unmet x(2) assumption. We presented the results by using tables and figures. RESULTS: From the total 1270 study participants, 1257 were included in the final analysis provided that a 98.97% response rate. Out of these, 10(0.8%) children were diagnosed with cancer. Regarding its types, two each, Acute Lymphocytic Leukemia, Wilms tumor, Hodgkin lymphoma, and one each non-Hodgkin lymphoma, Parotid cancer, Retinoblastoma, and Breast cancer were reported. The prevalence of childhood cancer was 0.9 and 0.7% among male and female children, respectively. CONCLUSIONS: Eight children diagnosed with cancer per 1000 children who visited the pediatric outpatient department. Even though childhood cancers have little attention from policymakers, the prevalence of childhood cancer remains prevalent. Therefore, researchers and policymakers shall give special emphasis to childhood cancer.
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spelling pubmed-79536432021-03-12 Prevalence of childhood Cancer among children attending referral hospitals of outpatient Department in Ethiopia Endalamaw, Aklilu Assimamaw, Nega Tezera Ayele, Tadesse Awoke Muche, Achenef Asmamaw Zeleke, Ejigu Gebeye Wondim, Amare Belay, Getaneh Mulualem Birhanu, Yeneabat Tazebew, Ashenafi Techane, Masresha Asmare Kassa, Selam Fisha Wubneh, Chalachew Adugna BMC Cancer Research Article INTRODUCTION: Childhood cancer is one of the leading causes of morbidity and mortality in the pediatrics age group. The problem affects both developed and developing countries. A high mortality rate has been observed in low-income counties. Despite its high fatality rate, less attention has been paid to the problem in developing countries, including Ethiopia. For this reason, childhood cancer is not well documented in the study setting. Therefore, we assessed the prevalence of childhood cancer in Ethiopia. METHODS: Institution based cross-sectional study design from January 1, 2019, to March 30, 2019, was conducted in the pediatrics treatment center. A systematic random sampling technique has used to select 1270 children in the pediatric outpatient department. The data were entered using Epi info version 7 and exported to SPSS version 20 for analysis. We checked model fitness for the advanced statistical methods, but it was difficult to proceed with logistic regression model to see the association between dependent and explanatory variables because of the unmet x(2) assumption. We presented the results by using tables and figures. RESULTS: From the total 1270 study participants, 1257 were included in the final analysis provided that a 98.97% response rate. Out of these, 10(0.8%) children were diagnosed with cancer. Regarding its types, two each, Acute Lymphocytic Leukemia, Wilms tumor, Hodgkin lymphoma, and one each non-Hodgkin lymphoma, Parotid cancer, Retinoblastoma, and Breast cancer were reported. The prevalence of childhood cancer was 0.9 and 0.7% among male and female children, respectively. CONCLUSIONS: Eight children diagnosed with cancer per 1000 children who visited the pediatric outpatient department. Even though childhood cancers have little attention from policymakers, the prevalence of childhood cancer remains prevalent. Therefore, researchers and policymakers shall give special emphasis to childhood cancer. BioMed Central 2021-03-12 /pmc/articles/PMC7953643/ /pubmed/33711955 http://dx.doi.org/10.1186/s12885-021-08014-0 Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Endalamaw, Aklilu
Assimamaw, Nega Tezera
Ayele, Tadesse Awoke
Muche, Achenef Asmamaw
Zeleke, Ejigu Gebeye
Wondim, Amare
Belay, Getaneh Mulualem
Birhanu, Yeneabat
Tazebew, Ashenafi
Techane, Masresha Asmare
Kassa, Selam Fisha
Wubneh, Chalachew Adugna
Prevalence of childhood Cancer among children attending referral hospitals of outpatient Department in Ethiopia
title Prevalence of childhood Cancer among children attending referral hospitals of outpatient Department in Ethiopia
title_full Prevalence of childhood Cancer among children attending referral hospitals of outpatient Department in Ethiopia
title_fullStr Prevalence of childhood Cancer among children attending referral hospitals of outpatient Department in Ethiopia
title_full_unstemmed Prevalence of childhood Cancer among children attending referral hospitals of outpatient Department in Ethiopia
title_short Prevalence of childhood Cancer among children attending referral hospitals of outpatient Department in Ethiopia
title_sort prevalence of childhood cancer among children attending referral hospitals of outpatient department in ethiopia
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953643/
https://www.ncbi.nlm.nih.gov/pubmed/33711955
http://dx.doi.org/10.1186/s12885-021-08014-0
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