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Dietary and lifestyle inflammatory scores are associated with increased risk of metabolic syndrome in Iranian adults
BACKGROUND: In the current study, we aimed to investigate the association of dietary inflammation scores (DIS) and lifestyle inflammation scores (LIS) with the risk of metabolic syndrome (MetS) in a prospective population-based study. METHODS: A total of 1625 participants without MetS were recruited...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953687/ https://www.ncbi.nlm.nih.gov/pubmed/33712064 http://dx.doi.org/10.1186/s13098-021-00648-1 |
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author | Farhadnejad, Hossein Parastouei, Karim Rostami, Hosein Mirmiran, Parvin Azizi, Fereidoun |
author_facet | Farhadnejad, Hossein Parastouei, Karim Rostami, Hosein Mirmiran, Parvin Azizi, Fereidoun |
author_sort | Farhadnejad, Hossein |
collection | PubMed |
description | BACKGROUND: In the current study, we aimed to investigate the association of dietary inflammation scores (DIS) and lifestyle inflammation scores (LIS) with the risk of metabolic syndrome (MetS) in a prospective population-based study. METHODS: A total of 1625 participants without MetS were recruited from among participants of the Tehran Lipid and Glucose Study(2006–2008) and followed a mean of 6.1 years. Dietary data of subjects were collected using a food frequency questionnaire at baseline to determine LIS and DIS. Multivariable logistic regression models, were used to calculate the odds ratio (ORs) and 95 % confidence interval (CI) of MetS across tertiles of DIS and LIS. RESULTS: Mean ± SD age of individuals (45.8 % men) was 37.5 ± 13.4 years. Median (25–75 interquartile range) DIS and LIS for all participants was 0.80 (− 2.94, 3.64) and 0.48 (− 0.18, − 0.89), respectively. During the study follow-up, 291 (17.9 %) new cases of MetS were identified. Based on the age and sex-adjusted model, a positive association was found between LIS (OR = 7.56; 95% CI 5.10–11.22, P for trend < 0.001) and risk of MetS, however, the association of DIS and risk of MetS development was not statistically significant (OR = 1.30;95% CI 0.93–1.80, P for trend = 0.127). In the multivariable model, after adjustment for confounding variables, including age, sex, body mass index, physical activity, smoking, and energy intake, the risk of MetS is increased across tertiles of DIS (OR = 1.59; 95% CI 1.09–2.33, P for trend = 0.015) and LIS(OR = 8.38; 95% CI 5.51–12.7, P for trend < 0.001). CONCLUSIONS: The findings of the current study showed that greater adherence to LIS and DIS, determined to indicate the inflammatory potential of diet and lifestyle, are associated with increased the risk of MetS. |
format | Online Article Text |
id | pubmed-7953687 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-79536872021-03-12 Dietary and lifestyle inflammatory scores are associated with increased risk of metabolic syndrome in Iranian adults Farhadnejad, Hossein Parastouei, Karim Rostami, Hosein Mirmiran, Parvin Azizi, Fereidoun Diabetol Metab Syndr Research BACKGROUND: In the current study, we aimed to investigate the association of dietary inflammation scores (DIS) and lifestyle inflammation scores (LIS) with the risk of metabolic syndrome (MetS) in a prospective population-based study. METHODS: A total of 1625 participants without MetS were recruited from among participants of the Tehran Lipid and Glucose Study(2006–2008) and followed a mean of 6.1 years. Dietary data of subjects were collected using a food frequency questionnaire at baseline to determine LIS and DIS. Multivariable logistic regression models, were used to calculate the odds ratio (ORs) and 95 % confidence interval (CI) of MetS across tertiles of DIS and LIS. RESULTS: Mean ± SD age of individuals (45.8 % men) was 37.5 ± 13.4 years. Median (25–75 interquartile range) DIS and LIS for all participants was 0.80 (− 2.94, 3.64) and 0.48 (− 0.18, − 0.89), respectively. During the study follow-up, 291 (17.9 %) new cases of MetS were identified. Based on the age and sex-adjusted model, a positive association was found between LIS (OR = 7.56; 95% CI 5.10–11.22, P for trend < 0.001) and risk of MetS, however, the association of DIS and risk of MetS development was not statistically significant (OR = 1.30;95% CI 0.93–1.80, P for trend = 0.127). In the multivariable model, after adjustment for confounding variables, including age, sex, body mass index, physical activity, smoking, and energy intake, the risk of MetS is increased across tertiles of DIS (OR = 1.59; 95% CI 1.09–2.33, P for trend = 0.015) and LIS(OR = 8.38; 95% CI 5.51–12.7, P for trend < 0.001). CONCLUSIONS: The findings of the current study showed that greater adherence to LIS and DIS, determined to indicate the inflammatory potential of diet and lifestyle, are associated with increased the risk of MetS. BioMed Central 2021-03-12 /pmc/articles/PMC7953687/ /pubmed/33712064 http://dx.doi.org/10.1186/s13098-021-00648-1 Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Farhadnejad, Hossein Parastouei, Karim Rostami, Hosein Mirmiran, Parvin Azizi, Fereidoun Dietary and lifestyle inflammatory scores are associated with increased risk of metabolic syndrome in Iranian adults |
title | Dietary and lifestyle inflammatory scores are associated with increased risk of metabolic syndrome in Iranian adults |
title_full | Dietary and lifestyle inflammatory scores are associated with increased risk of metabolic syndrome in Iranian adults |
title_fullStr | Dietary and lifestyle inflammatory scores are associated with increased risk of metabolic syndrome in Iranian adults |
title_full_unstemmed | Dietary and lifestyle inflammatory scores are associated with increased risk of metabolic syndrome in Iranian adults |
title_short | Dietary and lifestyle inflammatory scores are associated with increased risk of metabolic syndrome in Iranian adults |
title_sort | dietary and lifestyle inflammatory scores are associated with increased risk of metabolic syndrome in iranian adults |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953687/ https://www.ncbi.nlm.nih.gov/pubmed/33712064 http://dx.doi.org/10.1186/s13098-021-00648-1 |
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