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Type I IFNs and CD8 T cells increase intestinal barrier permeability after chronic viral infection
Intestinal barrier leakage constitutes a potential therapeutic target for many inflammatory diseases and represents a disease progression marker during chronic viral infections. However, the causes of altered gut barrier remain mostly unknown. Using murine infection with lymphocytic choriomeningitis...
Autores principales: | Labarta-Bajo, Lara, Nilsen, Steven P., Humphrey, Gregory, Schwartz, Tara, Sanders, Karenina, Swafford, Austin, Knight, Rob, Turner, Jerrold R., Zúñiga, Elina I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953738/ https://www.ncbi.nlm.nih.gov/pubmed/32880630 http://dx.doi.org/10.1084/jem.20192276 |
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