Tau assemblies do not behave like independently acting prion-like particles in mouse neural tissue

A fundamental property of infectious agents is their particulate nature: infectivity arises from independently-acting particles rather than as a result of collective action. Assemblies of the protein tau can exhibit seeding behaviour, potentially underlying the apparent spread of tau aggregation in...

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Detalles Bibliográficos
Autores principales: Miller, Lauren V. C., Mukadam, Aamir S., Durrant, Claire S., Vaysburd, Marina J., Katsinelos, Taxiarchis, Tuck, Benjamin J., Sanford, Sophie, Sheppard, Olivia, Knox, Claire, Cheng, Shi, James, Leo C., Coleman, Michael P., McEwan, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953780/
https://www.ncbi.nlm.nih.gov/pubmed/33712082
http://dx.doi.org/10.1186/s40478-021-01141-6

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