Cargando…

Divergent CPEB prion-like domains reveal different assembly mechanisms for a generic amyloid-like fold

BACKGROUND: Amyloids are ordered, insoluble protein aggregates, characterized by a cross-β sheet quaternary structure in which molecules in a β-strand conformation are stacked along the filament axis via intermolecular interactions. While amyloids are typically associated with pathological condition...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hervás, Rubén, del Carmen Fernández-Ramírez, María, Galera-Prat, Albert, Suzuki, Mari, Nagai, Yoshitaka, Bruix, Marta, Menéndez, Margarita, Laurents, Douglas V., Carrión-Vázquez, Mariano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953810/ https://www.ncbi.nlm.nih.gov/pubmed/33706787 http://dx.doi.org/10.1186/s12915-021-00967-9

Ejemplares similares

SUMOylation Is an Inhibitory Constraint that Regulates the Prion-like Aggregation and Activity of CPEB3
por: Drisaldi, Bettina, et al.
Publicado: (2015)

Conformational dynamics in the disordered region of human CPEB3 linked to memory consolidation
por: Ramírez de Mingo, D., et al.
Publicado: (2022)

Molecular Basis of Orb2 Amyloidogenesis and Blockade of Memory Consolidation
por: Hervás, Rubén, et al.
Publicado: (2016)

Common Features at the Start of the Neurodegeneration Cascade
por: Hervás, Rubén, et al.
Publicado: (2012)

Metamorphism in TDP-43 prion-like domain determines chaperone recognition
por: Carrasco, Jaime, et al.
Publicado: (2023)

Signal Transduction by a Fungal NOD-Like Receptor Based on Propagation of a Prion Amyloid Fold
por: Daskalov, Asen, et al.
Publicado: (2015)

Comparing the Folds of Prions and Other Pathogenic Amyloids
por: Flores-Fernández, José Miguel, et al.
Publicado: (2018)

On the Dependence of Prion and Amyloid Structure on the Folding Environment
por: Roterman, Irena, et al.
Publicado: (2021)

ApCPEB4, a non-prion domain containing homolog of ApCPEB, is involved in the initiation of long-term facilitation
por: Lee, Seung-Hee, et al.
Publicado: (2016)

Disease Transmission by Misfolded Prion-Protein Isoforms, Prion-Like Amyloids, Functional Amyloids and the Central Dogma
por: Daus, Martin L.
Publicado: (2016)

Characterization of Soft Amyloid Cores in Human Prion-Like Proteins
por: Batlle, Cristina, et al.
Publicado: (2017)

Regulation of sub-compartmental targeting and folding properties of the Prion-like protein Shadoo
por: Pepe, Anna, et al.
Publicado: (2017)

Structural transitions in Orb2 prion-like domain relevant for functional aggregation in memory consolidation
por: Oroz, Javier, et al.
Publicado: (2021)

The [Het-s] Prion, an Amyloid Fold as a Cell Death Activation Trigger
por: Saupe, Sven J., et al.
Publicado: (2012)

Prion-Like Behavior and Tau-dependent Cytotoxicity of Pyroglutamylated β-Amyloid
por: Nussbaum, Justin M., et al.
Publicado: (2012)

Key Points Concerning Amyloid Infectivity and Prion-Like Neuronal Invasion
por: Espargaró, Alba, et al.
Publicado: (2016)

Prion-like propagation of β-amyloid aggregates in the absence of APP overexpression
por: Ruiz-Riquelme, Alejandro, et al.
Publicado: (2018)

Prions and the like
por: Goedert, Michel
Publicado: (2014)

Phe-Gly motifs drive fibrillization of TDP-43’s prion-like domain condensates
por: Pantoja-Uceda, David, et al.
Publicado: (2021)

Classifying prion and prion-like phenomena
por: Harbi, Djamel, et al.
Publicado: (2014)

An Amyloid-Like Pathological Conformation of TDP-43 Is Stabilized by Hypercooperative Hydrogen Bonds
por: Mompeán, Miguel, et al.
Publicado: (2016)

Conservation of Prion-Like Composition and Sequence in Prion-Formers and Prion-Like Proteins of Saccharomyces cerevisiae
por: Su, Ting-Yi, et al.
Publicado: (2019)

Cytoplasmic Polyadenylation Element Binding Proteins CPEB1 and CPEB3 Regulate the Translation of FosB and Are Required for Maintaining Addiction-Like Behaviors Induced by Cocaine
por: Drisaldi, Bettina, et al.
Publicado: (2020)

Autism-like phenotype and risk gene-RNA deadenylation by CPEB4 mis-splicing
por: Parras, Alberto, et al.
Publicado: (2018)

Nanomechanics of tip-link cadherins
por: Oroz, Javier, et al.
Publicado: (2019)

The prion-like RNA-processing protein HNRPDL forms inherently toxic amyloid-like inclusion bodies in bacteria
por: Navarro, Susanna, et al.
Publicado: (2015)

Looking for a generic inhibitor of amyloid-like fibril formation among flavone derivatives
por: Šneideris, Tomas, et al.
Publicado: (2015)

PrionW: a server to identify proteins containing glutamine/asparagine rich prion-like domains and their amyloid cores
por: Zambrano, Rafael, et al.
Publicado: (2015)

Prions and Prion-Like Pathogens in Neurodegenerative Disorders
por: Peggion, Caterina, et al.
Publicado: (2014)

Prions, prion-like prionoids, and neurodegenerative disorders
por: Verma, Ashok
Publicado: (2016)

Mutant p53 Aggregates into Prion-like Amyloid Oligomers and Fibrils: IMPLICATIONS FOR CANCER
por: Ano Bom, Ana P. D., et al.
Publicado: (2012)

Elongation of Mouse Prion Protein Amyloid-Like Fibrils: Effect of Temperature and Denaturant Concentration
por: Milto, Katazyna, et al.
Publicado: (2014)

Induction of IAPP amyloid deposition and associated diabetic abnormalities by a prion-like mechanism
por: Mukherjee, Abhisek, et al.
Publicado: (2017)

Prion and Prion-like Diseases in Humans: Poster Abstracts
Publicado: (2013)

Emergence and evolution of yeast prion and prion-like proteins
por: An, Lu, et al.
Publicado: (2016)

Editorial: Prion and prion-like proteins in neurodegenerative diseases
por: Toni, Mattia, et al.
Publicado: (2022)

Generic amyloidogenicity of mammalian prion proteins from species susceptible and resistant to prions
por: Nyström, Sofie, et al.
Publicado: (2015)

Contribution of Specific Residues of the β-Solenoid Fold to HET-s Prion Function, Amyloid Structure and Stability
por: Daskalov, Asen, et al.
Publicado: (2014)

Prion-Like Domains in Phagobiota
por: Tetz, George, et al.
Publicado: (2017)

RNAs That Behave Like Prions
por: Mushegian, Arcady R., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_5q00fkit58ph311uo8401ji9bh