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Nature‐based botanical facial oil oxidative stress protection
INTRODUCTION: UV‐induced oxidative skin stress leads to cutaneous photoaging. The objective of these 2 studies was to evaluate a nature‐based botanical facial oil for the ability to decrease UV‐induced oxidative skin stress. METHODS: 22 females were enrolled in the UVA study, and 10 females were enr...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953896/ https://www.ncbi.nlm.nih.gov/pubmed/33350043 http://dx.doi.org/10.1111/jocd.13879 |
Sumario: | INTRODUCTION: UV‐induced oxidative skin stress leads to cutaneous photoaging. The objective of these 2 studies was to evaluate a nature‐based botanical facial oil for the ability to decrease UV‐induced oxidative skin stress. METHODS: 22 females were enrolled in the UVA study, and 10 females were enrolled in the UVB study. Skin chemiluminescence induced by UVA exposure was measured at baseline and after 2 weeks of daily topical application of the nature‐based facial oil was evaluated in study 1. In study 2, UVB‐induced erythema was measured after 8 weeks of twice‐daily topical application of the nature‐based facial oil to a photoprotected site followed by skin biopsy to evaluate sunburn cell formation. In both studies, the treatment response was compared to the response on untreated skin. RESULTS: The nature‐based facial oil significantly reduced skin chemiluminescence following UVA exposure, demonstrating antioxidant activity. The nature‐based facial oil also significantly reduced erythema formation following UVB exposure and resulted in reduced sunburn cell formation in 66.67% of subjects. CONCLUSION: Topical nature‐based facial oil can reduce UV‐induced oxidative cutaneous damage. |
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