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Nature‐based botanical facial oil oxidative stress protection

INTRODUCTION: UV‐induced oxidative skin stress leads to cutaneous photoaging. The objective of these 2 studies was to evaluate a nature‐based botanical facial oil for the ability to decrease UV‐induced oxidative skin stress. METHODS: 22 females were enrolled in the UVA study, and 10 females were enr...

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Autores principales: Diana Draelos, Zoe, Gunt, Hemali, Levy, Stanley B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953896/
https://www.ncbi.nlm.nih.gov/pubmed/33350043
http://dx.doi.org/10.1111/jocd.13879
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author Diana Draelos, Zoe
Gunt, Hemali
Levy, Stanley B.
author_facet Diana Draelos, Zoe
Gunt, Hemali
Levy, Stanley B.
author_sort Diana Draelos, Zoe
collection PubMed
description INTRODUCTION: UV‐induced oxidative skin stress leads to cutaneous photoaging. The objective of these 2 studies was to evaluate a nature‐based botanical facial oil for the ability to decrease UV‐induced oxidative skin stress. METHODS: 22 females were enrolled in the UVA study, and 10 females were enrolled in the UVB study. Skin chemiluminescence induced by UVA exposure was measured at baseline and after 2 weeks of daily topical application of the nature‐based facial oil was evaluated in study 1. In study 2, UVB‐induced erythema was measured after 8 weeks of twice‐daily topical application of the nature‐based facial oil to a photoprotected site followed by skin biopsy to evaluate sunburn cell formation. In both studies, the treatment response was compared to the response on untreated skin. RESULTS: The nature‐based facial oil significantly reduced skin chemiluminescence following UVA exposure, demonstrating antioxidant activity. The nature‐based facial oil also significantly reduced erythema formation following UVB exposure and resulted in reduced sunburn cell formation in 66.67% of subjects. CONCLUSION: Topical nature‐based facial oil can reduce UV‐induced oxidative cutaneous damage.
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spelling pubmed-79538962021-03-18 Nature‐based botanical facial oil oxidative stress protection Diana Draelos, Zoe Gunt, Hemali Levy, Stanley B. J Cosmet Dermatol Skin Care Articles INTRODUCTION: UV‐induced oxidative skin stress leads to cutaneous photoaging. The objective of these 2 studies was to evaluate a nature‐based botanical facial oil for the ability to decrease UV‐induced oxidative skin stress. METHODS: 22 females were enrolled in the UVA study, and 10 females were enrolled in the UVB study. Skin chemiluminescence induced by UVA exposure was measured at baseline and after 2 weeks of daily topical application of the nature‐based facial oil was evaluated in study 1. In study 2, UVB‐induced erythema was measured after 8 weeks of twice‐daily topical application of the nature‐based facial oil to a photoprotected site followed by skin biopsy to evaluate sunburn cell formation. In both studies, the treatment response was compared to the response on untreated skin. RESULTS: The nature‐based facial oil significantly reduced skin chemiluminescence following UVA exposure, demonstrating antioxidant activity. The nature‐based facial oil also significantly reduced erythema formation following UVB exposure and resulted in reduced sunburn cell formation in 66.67% of subjects. CONCLUSION: Topical nature‐based facial oil can reduce UV‐induced oxidative cutaneous damage. John Wiley and Sons Inc. 2020-12-21 2021-02 /pmc/articles/PMC7953896/ /pubmed/33350043 http://dx.doi.org/10.1111/jocd.13879 Text en © 2021 The Authors. Journal of Cosmetic Dermatology published by Wiley Periodicals LLC. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Skin Care Articles
Diana Draelos, Zoe
Gunt, Hemali
Levy, Stanley B.
Nature‐based botanical facial oil oxidative stress protection
title Nature‐based botanical facial oil oxidative stress protection
title_full Nature‐based botanical facial oil oxidative stress protection
title_fullStr Nature‐based botanical facial oil oxidative stress protection
title_full_unstemmed Nature‐based botanical facial oil oxidative stress protection
title_short Nature‐based botanical facial oil oxidative stress protection
title_sort nature‐based botanical facial oil oxidative stress protection
topic Skin Care Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7953896/
https://www.ncbi.nlm.nih.gov/pubmed/33350043
http://dx.doi.org/10.1111/jocd.13879
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