Cargando…

(99m)Tc-Radiolabeled Silica Nanocarriers for Targeted Detection and Treatment of HER2-Positive Breast Cancer

INTRODUCTION: The overexpression of Human Epidermal Growth Factor Receptor 2 (HER2) is usually associated with aggressive and infiltrating breast cancer (BC) phenotype, and metastases. Functionalized silica-based nanocarriers (SiNPs) can be labeled for in vivo imaging applications and loaded with ch...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rainone, Paolo, De Palma, Antonella, Sudati, Francesco, Roffia, Valentina, Rigamonti, Valentina, Salvioni, Lucia, Colombo, Miriam, Ripamonti, Marilena, Spinelli, Antonello Enrico, Mazza, Davide, Mauri, Pierluigi, Moresco, Rosa Maria, Prosperi, Davide, Belloli, Sara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954038/ https://www.ncbi.nlm.nih.gov/pubmed/33727808 http://dx.doi.org/10.2147/IJN.S276033

Ejemplares similares

Development of (99m)Tc-radiolabeled nanosilica for targeted detection of HER2-positive breast cancer
por: Rainone, Paolo, et al.
Publicado: (2017)

Hydroxyapatite and Titanium Dioxide Nanoparticles: Radiolabelling and In Vitro Stability of Prospective Theranostic Nanocarriers for (223)Ra and (99m)Tc
por: Suchánková, Petra, et al.
Publicado: (2020)

(99m)Tc-Radiolabeled TPGS Nanomicelles Outperform (99m)Tc-Sestamibi as Breast Cancer Imaging Agent
por: Tesan, Fiorella C., et al.
Publicado: (2019)

(99m)Tc-radiolabeled Levofloxacin and micelles as infection and inflammation imaging agents
por: Silindir-Gunay, Mine, et al.
Publicado: (2020)

Noninvasive imaging of radiolabeled exosome-mimetic nanovesicle using (99m)Tc-HMPAO
por: Hwang, Do Won, et al.
Publicado: (2015)

(99m)Tc-radiolabeled GE11-modified peptide for ovarian tumor targeting
por: Rahmanian, Najmeh, et al.
Publicado: (2017)

[(99m)Tc]Technetium-Labeled Niosomes: Radiolabeling, Quality Control, and In Vitro Evaluation
por: Ekinci, Meliha, et al.
Publicado: (2023)

Study of the Tissue Distribution of TLQP-21 in Mice Using [(18)F]JMV5763, a Radiolabeled Analog Prepared via [(18)F]Aluminum Fluoride Chelation Chemistry
por: Turolla, Elia A., et al.
Publicado: (2018)

Physicochemical and Biological Study of (99m)Tc and (68)Ga Radiolabelled Ciprofloxacin and Evaluation of [(99m)Tc]Tc-CIP as Potential Diagnostic Radiopharmaceutical for Diabetic Foot Syndrome Imaging
por: Koźmiński, Przemysław, et al.
Publicado: (2021)

Radiolabeling and Biological Evaluation of Novel (99m)Tc-Nitrido and (99m)Tc-Oxo Complexes with 4-Methoxy-(L)-Phenylalanine Dithiocarbamate for Tumor Imaging
por: Yin, Guangxing, et al.
Publicado: (2022)

Synthesis, Radiolabeling and Biological Evaluation of (99m)Tc-labeled Deoxyglucose Derivatives for Molecular Imaging
por: Sadeghzadeh, Masoud, et al.
Publicado: (2013)

(99m)Tc‐aprotinin – optimisation and validation of radiolabelling kits for routine preparation for diagnostic imaging of amyloidosis
por: Denholt, Charlotte, et al.
Publicado: (2016)

Synthesis and In Vitro Evaluation of Gold Nanoparticles Functionalized with Thiol Ligands for Robust Radiolabeling with (99m)Tc
por: Apostolopoulou, Adamantia, et al.
Publicado: (2021)

Evaluation of a new radiolabeled bombesin derivative with (99m)Tc as potential targeted tumor imaging agent
por: Sadeghzadeh, N., et al.
Publicado: (2013)

Radiolabeling and Preliminary Evaluation of (99m)Tc-Labeled DNA Cube Nanoparticles as Potential Tracers for SPECT Imaging
por: Duan, Xiaoyan, et al.
Publicado: (2021)

Tagging Efficiency of (99m) Tc-SC Radiolabeled Alternative Gastric Emptying Meals: A Quantitative Study
por: Pal, Deepak Kumar, et al.
Publicado: (2022)

Naphthol Blue Black and (99m)Tc-Labeled Mannosylated Human Serum Albumin ((99m)Tc-MSA) Conjugate as a Multimodal Lymph Node Mapping Nanocarrier
por: Lee, Ji Youn, et al.
Publicado: (2018)

Anti-CD20 Immunoglobulin G Radiolabeling with a (99m)Tc-Tricarbonyl Core: In Vitro and In Vivo Evaluations
por: Carpenet, Hélène, et al.
Publicado: (2015)

Radiolabeling and Preliminary Evaluation of (99m)Tc-Labeled DNA Cube Nanoparticles as Potential Tracers for SPECT Imaging [Corrigendum]
Publicado: (2022)

The New Radiolabeled Peptide (99m)TcEDDA/HYNIC-TOC: Is It a Feasible Choice for Diagnosing Gastroenteropancreatic NETs?
por: Gherghe, Mirela, et al.
Publicado: (2022)

Radiolabeling and Quantitative In Vivo SPECT/CT Imaging Study of Liposomes Using the Novel Iminothiolane-(99m)Tc-Tricarbonyl Complex
por: Varga, Zoltán, et al.
Publicado: (2017)

Brain targeting of zolmitriptan via transdermal terpesomes: statistical optimization and in vivo biodistribution study by (99m)Tc radiolabeling technique
por: Tawfik, Mai Ahmed, et al.
Publicado: (2023)

Comparison of [(99m)Tc]Tc-tilmanocept with [(99m)Tc]Tc-sulphur colloids and [(99m)Tc]Tc-albumin colloids for sentinel lymph node detection in patients with cutaneous malignancies of the head
por: Ooms, Mark, et al.
Publicado: (2022)

(18)F-Fluorocholine PET/CT, Tc-99m-MIBI and TC-99m-MDP SPECT/CT in Tertiary Hyperparathyroidism with Renal Osteodystrophy
por: Ferrari, Cristina, et al.
Publicado: (2020)

Recombinant Complement Receptor 2 Radiolabeled with [(99m)Tc(CO)(3)](+) : A Potential New Radiopharmaceutical for Imaging Activated Complement
por: Badar, Adam, et al.
Publicado: (2011)

Biological evaluation of new potential anticancer agent for tumour imaging and radiotherapy by two methods: (99m)Tc-radiolabelling and EPR spectroscopy
por: Karamalakova, Yanka, et al.
Publicado: (2014)

One-step, kit-based radiopharmaceuticals for molecular SPECT imaging: a versatile diphosphine chelator for (99m)Tc radiolabelling of peptides
por: Hungnes, Ingebjørg N., et al.
Publicado: (2021)

Comparison of 99mTc radiolabeled somatostatin antagonist with [(68) Ga]Ga-DOTA-TATE in a patient with advanced neuroendocrine tumor
por: Opalinska, Marta, et al.
Publicado: (2023)

Dual Radiolabeling as a Technique to Track Nanocarriers: The Case of Gold Nanoparticles
por: Rambanapasi, Clinton, et al.
Publicado: (2015)

Immune activity and biodistribution of polypeptide K237 and folic acid conjugated amphiphilic PEG-PLGA copolymer nanoparticles radiolabeled with (99m)Tc
por: He, Zelai, et al.
Publicado: (2016)

(99m)Tc Radiolabeled HA/TPGS-Based Curcumin-Loaded Nanoparticle for Breast Cancer Synergistic Theranostics: Design, in vitro and in vivo Evaluation
por: Huang, Chong, et al.
Publicado: (2020)

Clinical usefulness of (99m)Tc-HYNIC-TOC, (99m)Tc(V)-DMSA, and (99m)Tc-MIBI SPECT in the evaluation of pituitary adenomas
por: Vukomanovic, Vladimir R., et al.
Publicado: (2019)

The purity identification and radiolabeling of α-mangostin with technetium-99m
por: Muchtaridi, Muchtaridi, et al.
Publicado: (2020)

Head to head comparison of [(99m)Tc]Tc(CO)(3)(NTA) and [(99m)Tc]Tc-MAG3 in patients with suspected obstruction
por: Taylor, Andrew T., et al.
Publicado: (2021)

Pharmacokinetics of the phosphatidylserine tracers (99m)Tc-lactadherin and (99m)Tc-annexin V in pigs
por: Poulsen, Runa H, et al.
Publicado: (2013)

Altered [(99m)Tc]Tc-MDP biodistribution from neutron activation sourced (99)Mo
por: Demeter, Sandor, et al.
Publicado: (2018)

(99m)Tc-radiolabeled composites enabling in vivo imaging of arterial dispersal and retention of microspheres in the vascular network of rabbit lungs, liver, and liver tumors
por: Stephens, Ross W, et al.
Publicado: (2019)

Sentinel lymph node detection in oral cancer: a within-patient comparison between [(99m)Tc]Tc-tilmanocept and [(99m)Tc]Tc-nanocolloid
por: den Toom, Inne J., et al.
Publicado: (2020)

Comparing (99m)Tc-PSMA to (99m)Tc-MDP in Prostate Cancer Staging of the Skeletal System
por: Kabunda, Joseph, et al.
Publicado: (2021)

Radiolabeled Somatostatin Analogues for Diagnosis and Treatment of Neuroendocrine Tumors
por: Ambrosini, Valentina, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_cp989hij0q3rkrovjttf3m0hgs