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The potential shared role of inflammation in insulin resistance and schizophrenia: A bidirectional two-sample mendelian randomization study

BACKGROUND: Insulin resistance predisposes to cardiometabolic disorders, which are commonly comorbid with schizophrenia and are key contributors to the significant excess mortality in schizophrenia. Mechanisms for the comorbidity remain unclear, but observational studies have implicated inflammation...

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Detalles Bibliográficos
Autores principales: Perry, Benjamin I., Burgess, Stephen, Jones, Hannah J., Zammit, Stan, Upthegrove, Rachel, Mason, Amy M., Day, Felix R., Langenberg, Claudia, Wareham, Nicholas J., Jones, Peter B., Khandaker, Golam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954314/
https://www.ncbi.nlm.nih.gov/pubmed/33711016
http://dx.doi.org/10.1371/journal.pmed.1003455

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