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Biological impact of mutually exclusive exon switching

Alternative splicing can expand the diversity of proteomes. Homologous mutually exclusive exons (MXEs) originate from the same ancestral exon and result in polypeptides with similar structural properties but altered sequence. Why would some genes switch homologous exons and what are their biological...

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Detalles Bibliográficos
Autores principales:	Lam, Su Datt, Babu, M. Madan, Lees, Jonathan, Orengo, Christine A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954323/ https://www.ncbi.nlm.nih.gov/pubmed/33651795 http://dx.doi.org/10.1371/journal.pcbi.1008708

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