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Transcriptional analysis of islets of Langerhans from organ donors of different ages

Insulin secretion is impaired with increasing age. In this study, we aimed to determine whether aging induces specific transcriptional changes in human islets. Laser capture microdissection was used to extract pancreatic islet tissue from 37 deceased organ donors aged 1–81 years. The transcriptomes...

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Detalles Bibliográficos
Autores principales:	Seiron, Peter, Stenwall, Anton, Hedin, Anders, Granlund, Louise, Esguerra, Jonathan Lou S., Volkov, Petr, Renström, Erik, Korsgren, Olle, Lundberg, Marcus, Skog, Oskar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954335/ https://www.ncbi.nlm.nih.gov/pubmed/33711030 http://dx.doi.org/10.1371/journal.pone.0247888

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