Short-range template switching in great ape genomes explored using pair hidden Markov models

Many complex genomic rearrangements arise through template switch errors, which occur in DNA replication when there is a transient polymerase switch to an alternate template nearby in three-dimensional space. While typically investigated at kilobase-to-megabase scales, the genomic and evolutionary c...

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Detalles Bibliográficos
Autores principales: Walker, Conor R., Scally, Aylwyn, De Maio, Nicola, Goldman, Nick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954356/
https://www.ncbi.nlm.nih.gov/pubmed/33651813
http://dx.doi.org/10.1371/journal.pgen.1009221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954356/
https://www.ncbi.nlm.nih.gov/pubmed/33651813
http://dx.doi.org/10.1371/journal.pgen.1009221

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