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Human TERT promoter mutations as a prognostic biomarker in glioma

The TERT promoter (pTERT) mutations, C228T and C250T, play a significant role in malignant transformation by telomerase activation, oncogenesis and immortalisation of cells. C228T and C250T are emerging as important biomarkers in many cancers including glioblastoma multiforme (GBM), where the preval...

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Detalles Bibliográficos
Autores principales:	Powter, Branka, Jeffreys, Sarah A., Sareen, Heena, Cooper, Adam, Brungs, Daniel, Po, Joseph, Roberts, Tara, Koh, Eng-Siew, Scott, Kieran F., Sajinovic, Mila, Vessey, Joey Y., de Souza, Paul, Becker, Therese M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2021
Materias:	Review – Cancer Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954705/ https://www.ncbi.nlm.nih.gov/pubmed/33547950 http://dx.doi.org/10.1007/s00432-021-03536-3

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