Cargando…

Resveratrol induces PD-L1 expression through snail-driven activation of Wnt pathway in lung cancer cells

PURPOSE: Recent clinical trials with agents targeting immune checkpoint pathway have emerged as an important therapeutic approach for a broad range of cancer types. Resveratrol has been shown to possess cancer preventive and therapeutic effects and has potential to be chemotherapeutic agent/adjuvant...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Mengmeng, Li, Zongyu, Tao, Jianping, Hu, Hao, Li, Zilin, Zhang, Zhijian, Cheng, Feng, Sun, Yihang, Zhang, Yao, Yang, Jianke, Wei, Huijun, Wu, Zhihao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2021
Materias:	Original Article – Cancer Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954741/ https://www.ncbi.nlm.nih.gov/pubmed/33471184 http://dx.doi.org/10.1007/s00432-021-03510-z

Ejemplares similares

Upregulation of lactate-inducible snail protein suppresses oncogene-mediated senescence through p16(INK4a) inactivation
por: Li, Xiangrui, et al.
Publicado: (2018)

Wnt/β-catenin signaling as an emerging potential key pharmacological target in cholangiocarcinoma
por: Zhang, Guo-Feng, et al.
Publicado: (2020)

Baseline monocyte and its classical subtype may predict efficacy of PD-1/PD-L1 inhibitor in cancers
por: Shao, Yilin, et al.
Publicado: (2021)

Prostasin regulates PD-L1 expression in human lung cancer cells
por: Chen, Li-Mei, et al.
Publicado: (2021)

Urolithin A Inhibits Epithelial–Mesenchymal Transition in Lung Cancer Cells via P53-Mdm2-Snail Pathway
por: Cheng, Feng, et al.
Publicado: (2021)

PD-L1 regulates tumorigenesis and autophagy of ovarian cancer by activating mTORC signaling
por: Gao, Hongmin, et al.
Publicado: (2019)

WNT signaling and cancer stemness
por: Katoh, Masuko, et al.
Publicado: (2022)

Natural products and phytochemical nanoformulations targeting mitochondria in oncotherapy: an updated review on resveratrol
por: Ashrafizadeh, Milad, et al.
Publicado: (2020)

Prognostic value of programmed cell death ligand 1 (PD-L1) for hepatocellular carcinoma: a meta-analysis
por: Li, Xiao-Song, et al.
Publicado: (2020)

Remodeling of the tumor microenvironment using an engineered oncolytic vaccinia virus improves PD-L1 inhibition outcomes
por: Lou, Jiaying, et al.
Publicado: (2021)

Hyperbaric oxygen facilitates teniposide-induced cGAS-STING activation to enhance the antitumor efficacy of PD-1 antibody in HCC
por: Li, Kun, et al.
Publicado: (2022)

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy
por: Radaszkiewicz, Tomasz, et al.
Publicado: (2021)

Long non-coding RNA ROR1-AS1 induces tumorigenesis of colorectal cancer by affecting Wnt/β-catenin signaling pathway
por: Wang, Wei, et al.
Publicado: (2019)

Dehydroeffusol inhibits hypoxia-induced epithelial–mesenchymal transition in non-small cell lung cancer cells through the inactivation of Wnt/β-catenin pathway
por: Wei, Haitao, et al.
Publicado: (2020)

Risk of immune‐related pneumonitis for PD1/PD‐L1 inhibitors: Systematic review and network meta‐analysis
por: Huang, Yafang, et al.
Publicado: (2019)

PD-L1 expression in anogenital and oropharyngeal squamous cell carcinomas associated with different clinicopathological features, HPV status and prognosis: a meta-analysis
por: Qin, Yuan, et al.
Publicado: (2021)

PD‐1/PD‐L1 inhibitors‐based treatment for advanced renal cell carcinoma: Mechanisms affecting efficacy and combination therapies
por: Ding, Lei, et al.
Publicado: (2021)

20(S)-ginsenoside Rh2 as agent for the treatment of LMN-CRC via regulating epithelial–mesenchymal transition
por: Yuan, Yihang, et al.
Publicado: (2020)

Safety and Efficacy of PD‐1/PD‐L1 inhibitors combined with radiotherapy in patients with non‐small‐cell lung cancer: a systematic review and meta‐analysis
por: Geng, Yichao, et al.
Publicado: (2021)

Study and analysis of antitumor resistance mechanism of PD1/PD‐L1 immune checkpoint blocker
por: Wang, Zhengyi, et al.
Publicado: (2020)

Lactoferricin B reverses cisplatin resistance in head and neck squamous cell carcinoma cells through targeting PD‐L1
por: Zhang, Pei, et al.
Publicado: (2018)

NLRP3 augmented resistance to gemcitabine in triple-negative breast cancer cells via EMT/IL-1β/Wnt/β-catenin signaling pathway
por: Zheng, Qiao, et al.
Publicado: (2020)

Expression of SNAIL in accompanying PanIN is a key prognostic indicator in pancreatic ductal adenocarcinomas
por: Fujiwara, Sho, et al.
Publicado: (2019)

Lactate‐fueled oxidative metabolism drives DNA methyltransferase 1‐mediated transcriptional co‐activator with PDZ binding domain protein activation
por: Huang, Tao, et al.
Publicado: (2019)

Resveratrol inhibits the invasion and metastasis of colon cancer through reversal of epithelial- mesenchymal transition via the AKT/GSK-3β/Snail signaling pathway
por: Yuan, Li, et al.
Publicado: (2019)

Resveratrol inhibits the invasion and metastasis of colon cancer through reversal of epithelial-mesenchymal transition via the AKT/GSK-3β/Snail signaling pathway
por: Yuan, Li, et al.
Publicado: (2022)

Activation of hedgehog signaling in mesenchymal stem cells induces cartilage and bone tumor formation via Wnt/β-Catenin
por: Deng, Qi, et al.
Publicado: (2019)

14‐3‐3ζ promotes gliomas cells invasion by regulating Snail through the PI3K/AKT signaling
por: Li, Junjun, et al.
Publicado: (2019)

Prognostic significance of PD‐L2 expression in patients with oral squamous cell carcinoma—A comparison to the PD‐L1 expression profile
por: Weber, Manuel, et al.
Publicado: (2019)

Determining the optimal PD‐1/PD‐L1 inhibitors for the first‐line treatment of non‐small‐cell lung cancer with high‐level PD‐L1 expression in China
por: Teng, Meng‐Meng, et al.
Publicado: (2021)

MiR-27b-3p promotes migration and invasion in colorectal cancer cells by targeting HOXA10
por: Yang, Xiangling, et al.
Publicado: (2019)

Knockdown of LncRNA CRNDE suppresses proliferation and P-glycoprotein-mediated multidrug resistance in acute myelocytic leukemia through the Wnt/β-catenin pathway
por: Kang, Yiqing, et al.
Publicado: (2020)

Salvage nivolumab and ipilimumab after prior anti‐PD‐1/PD‐L1 therapy in metastatic renal cell carcinoma: A meta‐analysis
por: Yang, Yuanquan, et al.
Publicado: (2022)

GOLPH3 induces epithelial–mesenchymal transition via Wnt/β‐catenin signaling pathway in epithelial ovarian cancer
por: Sun, Jing, et al.
Publicado: (2017)

PD‐1/PD‐L1 Blockade Therapy in Advanced Non‐Small‐Cell Lung Cancer: Current Status and Future Directions
por: Xia, Liliang, et al.
Publicado: (2019)

Resveratrol stimulates StAR expression and progesterone production by GPER-mediated downregulation of Snail expression in human granulosa cells
por: Song, Tinglin, et al.
Publicado: (2023)

High number of PD‐1 positive intratumoural lymphocytes predicts survival benefit of cytokine‐induced killer cells for hepatocellular carcinoma patients
por: Chang, Boyang, et al.
Publicado: (2018)

Resveratrol promotes sensitization to Doxorubicin by inhibiting epithelial‐mesenchymal transition and modulating SIRT1/β‐catenin signaling pathway in breast cancer
por: Jin, Xiaoxia, et al.
Publicado: (2019)

Concordance of PD‐1 and PD‐L1 (B7‐H1) in paired primary and metastatic clear cell renal cell carcinoma
por: Eckel‐Passow, Jeanette E., et al.
Publicado: (2019)

Acetate promotes SNAI1 expression by ACSS2-mediated histone acetylation under glucose limitation in renal cell carcinoma cell
por: Yao, Lv, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_s8e1sqook2veujhsp0q73voo2v