The Emergence of Autism Symptoms Prior to 18 Months of Age: A Systematic Literature Review

Pre-diagnostic intervention for autism spectrum disorder (ASD) allows symptoms to be addressed as they emerge, often between six to 18 months, rather than after the full onset of the disorder. A systematic literature review, spanning the previous six years was conducted in order to provide an updated review looking at the earliest behavior symptoms of ASD. All included studies used a prospective experimental design, reported on symptoms that emerged before 18-months of age, exclusively in children who would later receive a diagnosis, and were assessed for quality. This review is the first to address this research question through the use of a systematic research design and extends the literature by following up on recommendations for future research from previous findings. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s10803-020-04618-w) contains supplementary material, which is available to authorized users.