Cargando…

Dual-specificity phosphatase 3 deletion promotes obesity, non-alcoholic steatohepatitis and hepatocellular carcinoma

Non-alcoholic fatty liver disease (NAFLD) is the most common chronic hepatic pathology in Western countries. It encompasses a spectrum of conditions ranging from simple steatosis to more severe and progressive non-alcoholic steatohepatitis (NASH) that can lead to hepatocellular carcinoma (HCC). Obes...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jacques, Sophie, Arjomand, Arash, Perée, Hélène, Collins, Patrick, Mayer, Alice, Lavergne, Arnaud, Wéry, Marie, Mni, Myriam, Hego, Alexandre, Thuillier, Virginie, Becker, Guillaume, Bahri, Mohamed Ali, Plenevaux, Alain, Di Valentin, Emmanuel, Oury, Cécile, Moutschen, Michel, Delvenne, Philippe, Paquot, Nicolas, Rahmouni, Souad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954796/ https://www.ncbi.nlm.nih.gov/pubmed/33712680 http://dx.doi.org/10.1038/s41598-021-85089-6

Ejemplares similares

Cervix carcinoma is associated with an up-regulation and nuclear localization of the dual-specificity protein phosphatase VHR
por: Henkens, Rachel, et al.
Publicado: (2008)

Kinetics and Persistence of the Cellular and Humoral Immune Responses to BNT162b2 mRNA Vaccine in SARS-CoV-2-Naive and -Experienced Subjects: Impact of Booster Dose and Breakthrough Infections
por: Desmecht, Salomé, et al.
Publicado: (2022)

Dusp3 deletion in mice promotes experimental lung tumour metastasis in a macrophage dependent manner
por: Vandereyken, Maud, et al.
Publicado: (2017)

DUSP3/VHR is a pro-angiogenic atypical dual-specificity phosphatase
por: Amand, Mathieu, et al.
Publicado: (2014)

Humanized mice as a useful model to study HIV-1 induced immune activation, its mechanisms and potential therapeutic approaches
por: Singh, Maneesh, et al.
Publicado: (2011)

New approach to determine the healthy immune variations by combining clustering methods
por: Liefferinckx, Claire, et al.
Publicado: (2021)

Advances in Pathophysiology of Calcific Aortic Valve Disease Propose Novel Molecular Therapeutic Targets
por: Hulin, Alexia, et al.
Publicado: (2018)

Deletion of Nardilysin Prevents the Development of Steatohepatitis and Liver Fibrotic Changes
por: Ishizu-Higashi, Shoko, et al.
Publicado: (2014)

Purinergic control of inflammation and thrombosis: Role of P2X1 receptors
por: Oury, Cécile, et al.
Publicado: (2014)

Phosphatase and tensin homologue deleted on chromosome 10
por: Abdulkareem, Imran Haruna, et al.
Publicado: (2013)

Downregulation of CD94/NKG2A inhibitory receptors on CD8(+ )T cells in HIV infection is more pronounced in subjects with detected viral load than in their aviraemic counterparts
por: Zeddou, Mustapha, et al.
Publicado: (2007)

MicroRNAs in Valvular Heart Diseases: Potential Role as Markers and Actors of Valvular and Cardiac Remodeling
por: Oury, Cécile, et al.
Publicado: (2016)

Prosthetic Aortic Valves: Challenges and Solutions
por: Musumeci, Lucia, et al.
Publicado: (2018)

Dual role of protein tyrosine phosphatase 1B in the progression and reversion of non-alcoholic steatohepatitis
por: González-Rodríguez, Águeda, et al.
Publicado: (2017)

Deletion of hepatic small heterodimer partner ameliorates development of nonalcoholic steatohepatitis in mice
por: Lee, Yoon-Kwang, et al.
Publicado: (2023)

Hepatic Molecular Signatures Highlight the Sexual Dimorphism of Nonalcoholic Steatohepatitis (NASH)
por: Vandel, Jimmy, et al.
Publicado: (2020)

Hepatocyte-Specific Deletion of Mouse Lamin A/C Leads to Male-Selective Steatohepatitis
por: Kwan, Raymond, et al.
Publicado: (2017)

Deletion of both p62 and Nrf2 spontaneously results in the development of nonalcoholic steatohepatitis
por: Akiyama, Kentaro, et al.
Publicado: (2017)

Pcsk9 Deletion Promotes Murine Nonalcoholic Steatohepatitis and Hepatic Carcinogenesis: Role of Cholesterol
por: Ioannou, George N., et al.
Publicado: (2021)

Protective Function of Mitogen‐Activated Protein Kinase Phosphatase 5 in Aging‐ and Diet‐Induced Hepatic Steatosis and Steatohepatitis
por: Tang, Peng, et al.
Publicado: (2019)

Preconditioning Effect of High-Intensity Interval Training (HIIT) and Berberine Supplementation on the Gene Expression of Angiogenesis Regulators and Caspase-3 Protein in the Rats with Myocardial Ischemia-Reperfusion (IR) Injury
por: Banaei, Parisa, et al.
Publicado: (2020)

Is Mitogen‐Activated Protein Kinase Phosphatase 5 a Solution to the Puzzle of the Mitogen‐Activated Protein Kinase Signal in Steatohepatitis?
por: Miura, Kouichi, et al.
Publicado: (2019)

Loss of phosphatase activity in PTEN (phosphatase and tensin homolog deleted on chromosome ten) results in endometrial carcinoma in humans: An in-silico study
por: Mondal, Sunil Kanti, et al.
Publicado: (2020)

Liver-specific deletion of RORα aggravates diet-induced nonalcoholic steatohepatitis by inducing mitochondrial dysfunction
por: Kim, Hyeon-Ji, et al.
Publicado: (2017)

Myeloid cell deletion of Aryl hydrocarbon Receptor Nuclear Translocator (ARNT) induces non-alcoholic steatohepatitis
por: Scott, Christopher, et al.
Publicado: (2019)

Deletion of the tyrosine phosphatase Shp2 in Sertoli cells causes infertility in mice
por: Hu, Xiaopeng, et al.
Publicado: (2015)

Treg-specific deletion of the phosphatase SHP-1 impairs control of inflammation in vivo
por: Gu, QinLei, et al.
Publicado: (2023)

An Improved Protocol for Efficient Engraftment in NOD/LTSZ-SCIDIL-2Rγ(NULL) Mice Allows HIV Replication and Development of Anti-HIV Immune Responses
por: Singh, Maneesh, et al.
Publicado: (2012)

Knockdown of hepatocyte Perilipin-3 mitigates hepatic steatosis and steatohepatitis caused by hepatocyte CGI-58 deletion in mice
por: Bao, Xinyu, et al.
Publicado: (2022)

Myeloid-specific deletion of chitinase-3-like 1 protein ameliorates murine diet-induced steatohepatitis progression
por: Kim, Andrea D., et al.
Publicado: (2023)

The phosphatase and tensin homologue deleted on chromosome 10 mediates radiosensitivity in head and neck cancer
por: Pattje, W J, et al.
Publicado: (2010)

Deletion of Dual Specificity Phosphatase 1 Does Not Predispose Mice to Increased Spontaneous Osteoarthritis
por: Pest, Michael Andrew, et al.
Publicado: (2015)

Deletion of inositol polyphosphate 4-phosphatase type-II B affects spermatogenesis in mice
por: Ceyhan, Yasemin, et al.
Publicado: (2020)

Deletion of Rap-phosphatases for quorum sensing control in Bacillus and its effect on surfactin production
por: Treinen, Chantal, et al.
Publicado: (2023)

Exercise against cocaine sensitization in mice: a [(18)F]fallypride micro-PET study
por: Becker, Guillaume, et al.
Publicado: (2021)

Tumor Microenvironment Modifications Recorded With IVIM Perfusion Analysis and DCE-MRI After Neoadjuvant Radiotherapy: A Preclinical Study
por: Lallemand, François, et al.
Publicado: (2021)

In-Depth Longitudinal Comparison of Clinical Specimens to Detect SARS-CoV-2
por: Defêche, Justine, et al.
Publicado: (2021)

Erratum: Elevated basal levels of circulating activated platelets predict ICU-acquired sepsis and mortality: a prospective study
por: Layios, N., et al.
Publicado: (2015)

Erratum: Prospective immune profiling in critically ill adults: before, during and after severe sepsis and septic shock
por: Layios, N., et al.
Publicado: (2015)

Liver-Specific Deletion of Phosphatase and Tensin Homolog Deleted on Chromosome 10 Significantly Ameliorates Chronic EtOH-Induced Increases in Hepatocellular Damage
por: Shearn, Colin T., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_umkirm3am9292fmd09c76f3scc