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Structural and functional characterization of a putative de novo gene in Drosophila

Comparative genomic studies have repeatedly shown that new protein-coding genes can emerge de novo from noncoding DNA. Still unknown is how and when the structures of encoded de novo proteins emerge and evolve. Combining biochemical, genetic and evolutionary analyses, we elucidate the function and s...

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Detalles Bibliográficos
Autores principales: Lange, Andreas, Patel, Prajal H., Heames, Brennen, Damry, Adam M., Saenger, Thorsten, Jackson, Colin J., Findlay, Geoffrey D., Bornberg-Bauer, Erich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7954818/
https://www.ncbi.nlm.nih.gov/pubmed/33712569
http://dx.doi.org/10.1038/s41467-021-21667-6