Integration of Alzheimer’s disease genetics and myeloid genomics identifies disease risk regulatory elements and genes

Genome-wide association studies (GWAS) have identified more than 40 loci associated with Alzheimer’s disease (AD), but the causal variants, regulatory elements, genes and pathways remain largely unknown, impeding a mechanistic understanding of AD pathogenesis. Previously, we showed that AD risk alle...

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Detalles Bibliográficos
Autores principales: Novikova, Gloriia, Kapoor, Manav, TCW, Julia, Abud, Edsel M., Efthymiou, Anastasia G., Chen, Steven X., Cheng, Haoxiang, Fullard, John F., Bendl, Jaroslav, Liu, Yiyuan, Roussos, Panos, Björkegren, Johan LM, Liu, Yunlong, Poon, Wayne W., Hao, Ke, Marcora, Edoardo, Goate, Alison M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955030/
https://www.ncbi.nlm.nih.gov/pubmed/33712570
http://dx.doi.org/10.1038/s41467-021-21823-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955030/
https://www.ncbi.nlm.nih.gov/pubmed/33712570
http://dx.doi.org/10.1038/s41467-021-21823-y

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