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Creb5 establishes the competence for Prg4 expression in articular cartilage
A hallmark of cells comprising the superficial zone of articular cartilage is their expression of lubricin, encoded by the Prg4 gene, that lubricates the joint and protects against the development of arthritis. Here, we identify Creb5 as a transcription factor that is specifically expressed in super...
Autores principales: | Zhang, Cheng-Hai, Gao, Yao, Jadhav, Unmesh, Hung, Han-Hwa, Holton, Kristina M., Grodzinsky, Alan J., Shivdasani, Ramesh A., Lassar, Andrew B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955038/ https://www.ncbi.nlm.nih.gov/pubmed/33712729 http://dx.doi.org/10.1038/s42003-021-01857-0 |
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