DNA methylation predicts age and provides insight into exceptional longevity of bats

Exceptionally long-lived species, including many bats, rarely show overt signs of aging, making it difficult to determine why species differ in lifespan. Here, we use DNA methylation (DNAm) profiles from 712 known-age bats, representing 26 species, to identify epigenetic changes associated with age...

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Detalles Bibliográficos
Autores principales: Wilkinson, Gerald S., Adams, Danielle M., Haghani, Amin, Lu, Ake T., Zoller, Joseph, Breeze, Charles E., Arnold, Bryan D., Ball, Hope C., Carter, Gerald G., Cooper, Lisa Noelle, Dechmann, Dina K. N., Devanna, Paolo, Fasel, Nicolas J., Galazyuk, Alexander V., Günther, Linus, Hurme, Edward, Jones, Gareth, Knörnschild, Mirjam, Lattenkamp, Ella Z., Li, Caesar Z., Mayer, Frieder, Reinhardt, Josephine A., Medellin, Rodrigo A., Nagy, Martina, Pope, Brian, Power, Megan L., Ransome, Roger D., Teeling, Emma C., Vernes, Sonja C., Zamora-Mejías, Daniel, Zhang, Joshua, Faure, Paul A., Greville, Lucas J., Herrera M., L. Gerardo, Flores-Martínez, José J., Horvath, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955057/
https://www.ncbi.nlm.nih.gov/pubmed/33712580
http://dx.doi.org/10.1038/s41467-021-21900-2

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