Primary ectocervical epithelial cells display lower permissivity to Chlamydia trachomatis than HeLa cells and a globally higher pro-inflammatory profile

The tumoral origin and extensive passaging of HeLa cells, a most commonly used cervical epithelial cell line, raise concerns on their suitability to study the cell responses to infection. The present study was designed to isolate primary epithelial cells from human ectocervix explants and characteri...

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Detalles Bibliográficos
Autores principales: Tang, Chongfa, Liu, Chang, Maffei, Benoit, Niragire, Béatrice, Cohen, Henri, Kane, Aminata, Donnadieu, Anne-Claire, Levy-Zauberman, Yael, Vernay, Thomas, Hugueny, Juliette, Vincens, Etienne, Louis-Sylvestre, Christine, Subtil, Agathe, Wu, Yongzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955086/
https://www.ncbi.nlm.nih.gov/pubmed/33712643
http://dx.doi.org/10.1038/s41598-021-85123-7

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