Cargando…

Water orientation and dynamics in the closed and open influenza B virus M2 proton channels

The influenza B M2 protein forms a water-filled tetrameric channel to conduct protons across the lipid membrane. To understand how channel water mediates proton transport, we have investigated the water orientation and dynamics using solid-state NMR spectroscopy and molecular dynamics (MD) simulatio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gelenter, Martin D., Mandala, Venkata S., Niesen, Michiel J. M., Sharon, Dina A., Dregni, Aurelio J., Willard, Adam P., Hong, Mei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955094/ https://www.ncbi.nlm.nih.gov/pubmed/33712696 http://dx.doi.org/10.1038/s42003-021-01847-2

Ejemplares similares

Atomic Structures of Closed and Open Influenza B M2 Proton Channel Reveal the Conduction Mechanism
por: Mandala, Venkata S., et al.
Publicado: (2020)

The Transmembrane Conformation of the Influenza B Virus M2 Protein in Lipid Bilayers
por: Mandala, Venkata S., et al.
Publicado: (2019)

The peptide hormone glucagon forms amyloid fibrils with two coexisting β-strand conformations
por: Gelenter, Martin D., et al.
Publicado: (2019)

Structure and Drug Binding of the SARS-CoV-2 Envelope Protein in Phospholipid Bilayers
por: Mandala, Venkata S., et al.
Publicado: (2020)

Structure and drug binding of the SARS-CoV-2 envelope protein transmembrane domain in lipid bilayers
por: Mandala, Venkata S., et al.
Publicado: (2020)

Orientations and Proximities of the Extracellular Ends of Transmembrane Helices S0 and S4 in Open and Closed BK Potassium Channels
por: Niu, Xiaowei, et al.
Publicado: (2013)

Atomic structure of the open SARS-CoV-2 E viroporin
por: Medeiros-Silva, João, et al.
Publicado: (2023)

High-pH structure of EmrE reveals the mechanism of proton-coupled substrate transport
por: Shcherbakov, Alexander A., et al.
Publicado: (2022)

Voltage-sensor movements in the Eag Kv channel under an applied electric field
por: Mandala, Venkata Shiva, et al.
Publicado: (2022)

Unlocking the mechanisms of HCN channel gating with locked-open and locked-closed channels
por: Trudeau, Matthew C.
Publicado: (2012)

The membrane electric field regulates the PIP(2)-binding site to gate the KCNQ1 channel
por: Mandala, Venkata Shiva, et al.
Publicado: (2023)

Solution structure and functional analysis of the influenza B proton channel
por: Wang, Junfeng, et al.
Publicado: (2009)

Oriented chiral water wires in artificial transmembrane channels
por: Kocsis, Istvan, et al.
Publicado: (2018)

Cooperative Transition between Open and Closed Conformations in Potassium Channels
por: Haliloglu, Turkan, et al.
Publicado: (2008)

Opening and Closing of KcnkØ Potassium Leak Channels Is Tightly Regulated
por: Zilberberg, Noam, et al.
Publicado: (2000)

Charge Movement Associated with the Opening and Closing of the Activation Gates of the Na Channels
por: Armstrong, Clay M., et al.
Publicado: (1974)

Barium blockade of the KcsA channel in open and closed conformation datasets
por: Rohaim, Ahmed, et al.
Publicado: (2020)

Open and closed states of Candida antarctica lipase B: protonation and the mechanism of interfacial activation(1)
por: Stauch, Benjamin, et al.
Publicado: (2015)

Amyloid fibril structures of tau: Conformational plasticity of the second microtubule-binding repeat
por: El Mammeri, Nadia, et al.
Publicado: (2023)

Structures of Rhodopseudomonas palustris RC-LH1 complexes with open or closed quinone channels
por: Swainsbury, David J. K., et al.
Publicado: (2021)

Proton-spin orientation
por: Borghini, Michel
Publicado: (1968)

Conformational heterogeneity in closed and open states of the KcsA potassium channel in lipid bicelles
por: Kim, Dorothy M., et al.
Publicado: (2016)

Orientation of non-spherical protonated water clusters revealed by infrared absorption dichroism
por: Daldrop, Jan O., et al.
Publicado: (2018)

Kinetics of Proton Transport into Influenza Virions by the Viral M2 Channel
por: Ivanovic, Tijana, et al.
Publicado: (2012)

Reaction of tetraethylammonium with the open and closed conformations of the acetylcholine receptor ionic channel complex
Publicado: (1979)

PLG-007 and Its Active Component Galactomannan-α Competitively Inhibit Enzymes That Hydrolyze Glucose Polymers
por: Miller, Michelle C., et al.
Publicado: (2022)

Mechanism of action of K channel openers on skeletal muscle KATP channels. Interactions with nucleotides and protons
Publicado: (1996)

Recombinant Expression and Chemical Amidation of Isotopically Labeled Native Melittin
por: Gelenter, Martin D., et al.
Publicado: (2023)

Kinetics of the Opening and Closing of Individual Excitability-Inducing Material Channels in a Lipid Bilayer
por: Ehrenstein, Gerald, et al.
Publicado: (1974)

Structural model of the open–closed–inactivated cycle of prokaryotic voltage-gated sodium channels
por: Bagnéris, Claire, et al.
Publicado: (2015)

Cystic Fibrosis Transmembrane Conductance Regulator (CFTR): CLOSED AND OPEN STATE CHANNEL MODELS
por: Corradi, Valentina, et al.
Publicado: (2015)

Deglycosylation of Shaker K(V) channels affects voltage sensing and the open–closed transition
por: Lopez-Rodriguez, Angelica, et al.
Publicado: (2018)

Hydrophobic gasket mutation produces gating pore currents in closed human voltage-gated proton channels
por: Banh, Richard, et al.
Publicado: (2019)

Water, proton, and urea transport in toad bladder endosomes that contain the vasopressin-sensitive water channel
Publicado: (1990)

Open Session and Closing
por: CERN. Geneva
Publicado: (2018)

Opening closed pores
por: LeBrasseur, Nicole
Publicado: (2004)

Closing Open Medicine
por: Kendall, Claire, et al.
Publicado: (2014)

Microtubule-binding core of the tau protein
por: El Mammeri, Nadia, et al.
Publicado: (2022)

Water Orientation at the Calcite-Water Interface
por: Söngen, Hagen, et al.
Publicado: (2021)

Evidence for adjustable bandwidth orientation channels
por: Taylor, Christopher P., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_rro38vlbac5qcmla44pjekhds9