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Water orientation and dynamics in the closed and open influenza B virus M2 proton channels

The influenza B M2 protein forms a water-filled tetrameric channel to conduct protons across the lipid membrane. To understand how channel water mediates proton transport, we have investigated the water orientation and dynamics using solid-state NMR spectroscopy and molecular dynamics (MD) simulatio...

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Detalles Bibliográficos
Autores principales:	Gelenter, Martin D., Mandala, Venkata S., Niesen, Michiel J. M., Sharon, Dina A., Dregni, Aurelio J., Willard, Adam P., Hong, Mei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955094/ https://www.ncbi.nlm.nih.gov/pubmed/33712696 http://dx.doi.org/10.1038/s42003-021-01847-2

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