Interleukin 12p40 Deficiency Promotes Abdominal Aortic Aneurysm by Activating CCN2/MMP2 Pathways

BACKGROUND: Development of abdominal aortic aneurysm (AAA) is associated with proinflammatory cytokines including interleukin‐12 (IL12). Deficiency of interleukin 12p40 (IL12p40) increases localized fibrotic events by promoting TGFβ2 (transforming growth factor β)‐dependent anti‐inflammatory respons...

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Detalles Bibliográficos
Autores principales: Sharma, Neekun, Hans, Chetan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955443/
https://www.ncbi.nlm.nih.gov/pubmed/33470127
http://dx.doi.org/10.1161/JAHA.120.017633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955443/
https://www.ncbi.nlm.nih.gov/pubmed/33470127
http://dx.doi.org/10.1161/JAHA.120.017633

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