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Paroxetine Attenuates Cardiac Hypertrophy Via Blocking GRK2 and ADRB1 Interaction in Hypertension

BACKGROUND: ADRB1 (adrenergic receptor beta 1) responds to neuroendocrine stimulations, which have great implications in hypertension. GRK2 (G protein‐coupled receptor kinase 2) is an essential regulator for many G protein‐coupled receptors and subsequent cell signaling cascades, but its role as a r...

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Detalles Bibliográficos
Autores principales: Sun, Xuejing, Zhou, Mengli, Wen, Gaiyan, Huang, Yun, Wu, Junru, Peng, Liping, Jiang, Weihong, Yuan, Hong, Lu, Yao, Cai, Jingjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955481/
https://www.ncbi.nlm.nih.gov/pubmed/33372534
http://dx.doi.org/10.1161/JAHA.120.016364

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