Cargando…

Pentosan polysulfate sodium for Ross River virus-induced arthralgia: a phase 2a, randomized, double-blind, placebo-controlled study

BACKGROUND: Alphaviruses, such as Ross River (RRV) and chikungunya virus (CHIKV), cause significant global morbidity, with outbreaks of crippling joint inflammation and pain, leaving patients incapacitated for months to years. With no available vaccine or specific therapeutic for any alphaviral dise...

Descripción completa

Detalles Bibliográficos
Autores principales:	Krishnan, Ravi, Duiker, Melanie, Rudd, Penny A., Skerrett, Donna, Pollard, James G. D., Siddel, Carolyn, Rifat, Rifat, Ng, Jennifer H. K., Georgius, Peter, Hererro, Lara J., Griffin, Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955617/ https://www.ncbi.nlm.nih.gov/pubmed/33711991 http://dx.doi.org/10.1186/s12891-021-04123-w

Ejemplares similares

Maculopathy caused by pentosan polysulfate
por: Rosenberg, Daniel, et al.
Publicado: (2021)

Pentosan Polysulfate: A Novel Therapy for the Mucopolysaccharidoses
por: Schuchman, Edward H., et al.
Publicado: (2013)

Visual Function in Pentosan Polysulfate Sodium Maculopathy
por: Lyons, Riley J., et al.
Publicado: (2020)

Pentosan polysulfate sodium prevents functional decline in chikungunya infected mice by modulating growth factor signalling and lymphocyte activation
por: Rudd, Penny A., et al.
Publicado: (2021)

Potential Anti-SARS-CoV-2 Activity of Pentosan Polysulfate and Mucopolysaccharide Polysulfate
por: Zhang, Fuming, et al.
Publicado: (2022)

Maculopathie causée par le polysulfate de pentosan
por: Rosenberg, Daniel, et al.
Publicado: (2021)

Pentosan polysulfate regulates hepcidin expression in native Mongolian horses
por: WIJEKOON, Suranji, et al.
Publicado: (2022)

Pentosan Polysulfate Affords Pleotropic Protection to Multiple Cells and Tissues
por: Smith, Margaret M., et al.
Publicado: (2023)

A case of pentosan polysulfate maculopathy originally diagnosed as stargardt disease
por: Vora, Robin A., et al.
Publicado: (2020)

Maculopathy Secondary to Pentosan Polysulfate Use: A Single-Center Experience
por: Kalbag, Neil S, et al.
Publicado: (2021)

Type 3 macular neovascularization in a patient with pentosan polysulfate maculopathy
por: Bousquet, Elodie, et al.
Publicado: (2022)

Pentosan Polysulfate: Oral Versus Subcutaneous Injection in Mucopolysaccharidosis Type I Dogs
por: Simonaro, Calogera M., et al.
Publicado: (2016)

Safety Study of Sodium Pentosan Polysulfate for Adult Patients with Mucopolysaccharidosis Type II
por: Orii, Kenji, et al.
Publicado: (2019)

Acute and severe haemorrhage following pentosan polysulfate injection in a Cornish Rex
por: Tong, Miranda X, et al.
Publicado: (2021)

Pentosan Polysulfate Sodium-Associated Pigmentary Retinopathy: Risk Factors and Fundus Findings
por: Leung, Ella H, et al.
Publicado: (2021)

Efficacy of Pentosan Polysulfate Treatment in Patients with Interstitial Cystitis/Bladder Pain Syndrome
por: Arıkan, Mehmet Gürkan, et al.
Publicado: (2023)

Effects of pentosan polysulfate and polysulfated glycosaminoglycan on chondrogenesis of canine bone marrow-derived mesenchymal stem cells in alginate and micromass culture
por: BWALYA, Eugene C., et al.
Publicado: (2017)

Increased Proinflammatory Cytokine Levels in Prolonged Arthralgia in Ross River Virus Infection
por: Tappe, Dennis, et al.
Publicado: (2017)

Broad Th2 neutralization and anti‐inflammatory action of pentosan polysulfate sodium in experimental allergic rhinitis
por: Sanden, Caroline, et al.
Publicado: (2017)

Sodium pentosan polysulfate resulted in cartilage improvement in knee osteoarthritis - An open clinical trial-
por: Kumagai, Kenji, et al.
Publicado: (2010)

Efficacy of pentosan polysulfate in in vitro models of lysosomal storage disorders: Fabry and Gaucher Disease
por: Crivaro, Andrea N., et al.
Publicado: (2019)

Postmortem findings in a case of variant Creutzfeldt-Jakob disease treated with intraventricular pentosan polysulfate
por: Newman, P K, et al.
Publicado: (2014)

The effect of Hydrodistension in combination with Pentosan Polysulfate on treatment outcomes and compliance in the treatment of bladder pain syndrome
por: Simsir, Adnan, et al.
Publicado: (2019)

Xylan Prebiotics and the Gut Microbiome Promote Health and Wellbeing: Potential Novel Roles for Pentosan Polysulfate
por: Smith, Margaret M., et al.
Publicado: (2022)

An unusual case of rapid resolution of bilateral vitelliform deposits after discontinuation of pentosan polysulfate sodium
por: Kalaw, Fritz Gerald P., et al.
Publicado: (2023)

Pentosan Polysulfate Inhibits Attachment and Infection by SARS-CoV-2 In Vitro: Insights into Structural Requirements for Binding
por: Bertini, Sabrina, et al.
Publicado: (2022)

Inhibitory effects of sodium pentosan polysulfate on formation and function of osteoclasts derived from canine bone marrow
por: Wijekoon, H. M. Suranji, et al.
Publicado: (2018)

Safety and efficacy of pentosan polysulfate in patients with bladder pain syndrome/interstitial cystitis: a multicenter, double–blind, placebo–controlled, randomized study
por: Kasyan, George, et al.
Publicado: (2021)

Pentosan polysulfate promotes proliferation and chondrogenic differentiation of adult human bone marrow-derived mesenchymal precursor cells
por: Ghosh, Peter, et al.
Publicado: (2010)

Dose Responsive Effects of Subcutaneous Pentosan Polysulfate Injection in Mucopolysaccharidosis Type VI Rats and Comparison to Oral Treatment
por: Frohbergh, Michael, et al.
Publicado: (2014)

Identification of Patients with Pentosan Polysulfate Sodium-Associated Maculopathy through Screening of the Electronic Medical Record at an Academic Center
por: Higgins, Kendall, et al.
Publicado: (2020)

Pentosan polysulfate regulates hepcidin 1-facilitated formation and function of osteoclast derived from canine bone marrow
por: Wijekoon, Suranji, et al.
Publicado: (2022)

Transient Postoperative Hemorrhage from Elbow Arthroscopy Portals following Intra-Articular Pentosan Polysulfate Sodium Injection
por: Parker, Lindsay A., et al.
Publicado: (2022)

Role of oral pentosan polysulfate in Bacillus Calmette–Guérin therapy in patients with non-muscle-invasive bladder cancer
por: Lee, Ho Yeon, et al.
Publicado: (2022)

The effect of pentosan polysulfate sodium for improving dyslipidaemia and knee pain in people with knee osteoarthritis: A pilot study
por: Liu, Xiaoqian, et al.
Publicado: (2023)

Anti-inflammatory actions of Pentosan polysulfate sodium in a mouse model of influenza virus A/PR8/34-induced pulmonary inflammation
por: Krishnan, Ravi, et al.
Publicado: (2023)

Pentosan polysulfate increases affinity between ADAMTS-5 and TIMP-3 through formation of an electrostatically driven trimolecular complex
por: Troeberg, Linda, et al.
Publicado: (2012)

Effects of pentosan polysulfate on cell proliferation, cell cycle progression and cyclin-dependent kinases expression in canine articular chondrocytes
por: AKARAPHUTIPORN, Ekkapol, et al.
Publicado: (2020)

Pentosan polysulfate in patients with bladder pain syndrome/interstitial cystitis with Hunner’s lesions or glomerulations: systematic review and meta-analysis
por: Grigoryan, Bagrat, et al.
Publicado: (2022)

A post-trial follow-up study of pentosan polysulfate monotherapy on preventing recurrent urinary tract infection in women
por: Lee, Yuan-Ju, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_db2jvpn4d8absjd21h7nc1kq2o