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Density Peak clustering of protein sequences associated to a Pfam clan reveals clear similarities and interesting differences with respect to manual family annotation
BACKGROUND: The identification of protein families is of outstanding practical importance for in silico protein annotation and is at the basis of several bioinformatic resources. Pfam is possibly the most well known protein family database, built in many years of work by domain experts with extensiv...
Autores principales: | Russo, Elena Tea, Laio, Alessandro, Punta, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955657/ https://www.ncbi.nlm.nih.gov/pubmed/33711918 http://dx.doi.org/10.1186/s12859-021-04013-x |
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