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Density Peak clustering of protein sequences associated to a Pfam clan reveals clear similarities and interesting differences with respect to manual family annotation

BACKGROUND: The identification of protein families is of outstanding practical importance for in silico protein annotation and is at the basis of several bioinformatic resources. Pfam is possibly the most well known protein family database, built in many years of work by domain experts with extensiv...

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Detalles Bibliográficos
Autores principales: Russo, Elena Tea, Laio, Alessandro, Punta, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955657/
https://www.ncbi.nlm.nih.gov/pubmed/33711918
http://dx.doi.org/10.1186/s12859-021-04013-x

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