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COVID-19 dynamics considering the influence of hospital infrastructure: an investigation into Brazilian scenarios
COVID-19 dynamics is one of the most relevant subjects nowadays, and, in this regard, mathematical modeling and numerical simulations are of special interest. This paper describes COVID-19 dynamics based on a novel version of the susceptible–exposed–infectious–removed model. Removed population is sp...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955701/ https://www.ncbi.nlm.nih.gov/pubmed/33746362 http://dx.doi.org/10.1007/s11071-021-06323-4 |
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author | Pacheco, Pedro M. C. L. Savi, Marcelo A. Savi, Pedro V. |
author_facet | Pacheco, Pedro M. C. L. Savi, Marcelo A. Savi, Pedro V. |
author_sort | Pacheco, Pedro M. C. L. |
collection | PubMed |
description | COVID-19 dynamics is one of the most relevant subjects nowadays, and, in this regard, mathematical modeling and numerical simulations are of special interest. This paper describes COVID-19 dynamics based on a novel version of the susceptible–exposed–infectious–removed model. Removed population is split into recovered and death populations allowing a better comprehension of real situations. Besides, the total population is reduced based on the number of deaths. Hospital infrastructure is also included into the mathematical description allowing the consideration of collapse scenarios. Initially, a model verification is carried out calibrating system parameters with data from China outbreak that is considered a benchmark due the availability of data for the entire cycle. Afterward, Brazil outbreak is of concern, calibrating the model and developing numerical simulations. Results show several scenarios highlighting the importance of social isolation and hospital infrastructure. System dynamics has a strong sensitivity to transmission rate showing the importance of numerical simulations to guide public health decision strategies. Results also show that complex dynamical responses can emerge due to the oscillations of the transmission rate, being associated with distinct infection subsequent waves. |
format | Online Article Text |
id | pubmed-7955701 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer Netherlands |
record_format | MEDLINE/PubMed |
spelling | pubmed-79557012021-03-15 COVID-19 dynamics considering the influence of hospital infrastructure: an investigation into Brazilian scenarios Pacheco, Pedro M. C. L. Savi, Marcelo A. Savi, Pedro V. Nonlinear Dyn Original Paper COVID-19 dynamics is one of the most relevant subjects nowadays, and, in this regard, mathematical modeling and numerical simulations are of special interest. This paper describes COVID-19 dynamics based on a novel version of the susceptible–exposed–infectious–removed model. Removed population is split into recovered and death populations allowing a better comprehension of real situations. Besides, the total population is reduced based on the number of deaths. Hospital infrastructure is also included into the mathematical description allowing the consideration of collapse scenarios. Initially, a model verification is carried out calibrating system parameters with data from China outbreak that is considered a benchmark due the availability of data for the entire cycle. Afterward, Brazil outbreak is of concern, calibrating the model and developing numerical simulations. Results show several scenarios highlighting the importance of social isolation and hospital infrastructure. System dynamics has a strong sensitivity to transmission rate showing the importance of numerical simulations to guide public health decision strategies. Results also show that complex dynamical responses can emerge due to the oscillations of the transmission rate, being associated with distinct infection subsequent waves. Springer Netherlands 2021-03-13 2021 /pmc/articles/PMC7955701/ /pubmed/33746362 http://dx.doi.org/10.1007/s11071-021-06323-4 Text en © The Author(s), under exclusive licence to Springer Nature B.V. part of Springer Nature 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Original Paper Pacheco, Pedro M. C. L. Savi, Marcelo A. Savi, Pedro V. COVID-19 dynamics considering the influence of hospital infrastructure: an investigation into Brazilian scenarios |
title | COVID-19 dynamics considering the influence of hospital infrastructure: an investigation into Brazilian scenarios |
title_full | COVID-19 dynamics considering the influence of hospital infrastructure: an investigation into Brazilian scenarios |
title_fullStr | COVID-19 dynamics considering the influence of hospital infrastructure: an investigation into Brazilian scenarios |
title_full_unstemmed | COVID-19 dynamics considering the influence of hospital infrastructure: an investigation into Brazilian scenarios |
title_short | COVID-19 dynamics considering the influence of hospital infrastructure: an investigation into Brazilian scenarios |
title_sort | covid-19 dynamics considering the influence of hospital infrastructure: an investigation into brazilian scenarios |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955701/ https://www.ncbi.nlm.nih.gov/pubmed/33746362 http://dx.doi.org/10.1007/s11071-021-06323-4 |
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