Complete Response to Pembrolizumab in Advanced Colon Cancer Harboring Somatic POLE F367S Mutation with Microsatellite Stability Status: A Case Study

BACKGROUND: Polymerase epsilon (POLE) mutations are considered as one of the most potential and promising biomarkers for immune checkpoint inhibitors (ICIs) in patients with colorectal cancer. However, the treatment of ICIs sometimes also resulted in unsatisfactory results in patients with POLE muta...

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Detalles Bibliográficos
Autores principales: Chen, Jianxin, Lou, Haizhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955730/
https://www.ncbi.nlm.nih.gov/pubmed/33727829
http://dx.doi.org/10.2147/OTT.S300987

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955730/
https://www.ncbi.nlm.nih.gov/pubmed/33727829
http://dx.doi.org/10.2147/OTT.S300987

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