Cargando…

11β-Hydroxylase (CYP11B1) gene variants and new-onset depression in later life

BACKGROUND: Cumulative exposure to high glucocorticoid levels is detrimental for the brain and may have particular implications in later life. A feature of late-life depression is increased cortisol secretion. Variants in the CYP11B1 gene, which codes for the enzyme responsible for cortisol synthesi...

Descripción completa

Detalles Bibliográficos
Autores principales: Ancelin, Marie-Laure, Norton, Joanna, Ritchie, Karen, Chaudieu, Isabelle, Ryan, Joanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Joule Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7955840/
https://www.ncbi.nlm.nih.gov/pubmed/33245660
http://dx.doi.org/10.1503/jpn.190177