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Type I interferon response-related microglial Mef2c deregulation at the onset of Alzheimer’s pathology in 5×FAD mice

Alzheimer’s disease (AD) is a chronic neurodegenerative disorder with multifactorial etiology. The role of microglia in the pathogenesis of AD has been increasingly recognized in recent years; however, the detailed mechanisms shaping microglial phenotypes in AD-relevant pathological settings remain...

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Detalles Bibliográficos
Autores principales: Xue, Feng, Tian, Jing, Yu, Chunxiao, Du, Heng, Guo, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956132/
https://www.ncbi.nlm.nih.gov/pubmed/33540048
http://dx.doi.org/10.1016/j.nbd.2021.105272