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FOXC1 Downregulates Nanog Expression by Recruiting HDAC2 to Its Promoter in F9 Cells Treated by Retinoic Acid

FOXC1, a transcription factor involved in cell differentiation and embryogenesis, is demonstrated to be a negative regulator of Nanog in this study. FOXC1 is up-regulated in retinoic acid-induced differentiation of F9 Embryonal Carcinoma (EC) cells; furthermore, FOXC1 specifically inhibits the core...

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Detalles Bibliográficos
Autores principales:	Xue, Hongni, Liu, Fayang, Ai, Zhiying, Ke, Jie, Yu, Mengying, Chen, Bingxue, Guo, Zekun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956269/ https://www.ncbi.nlm.nih.gov/pubmed/33668324 http://dx.doi.org/10.3390/ijms22052255

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