Targeting Insulin-Degrading Enzyme in Insulin Clearance

Hepatic insulin clearance, a physiological process that in response to nutritional cues clears ~50–80% of circulating insulin, is emerging as an important factor in our understanding of the pathogenesis of type 2 diabetes mellitus (T2DM). Insulin-degrading enzyme (IDE) is a highly conserved Zn(2+)-m...

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Detalles Bibliográficos
Autores principales: Leissring, Malcolm A., González-Casimiro, Carlos M., Merino, Beatriz, Suire, Caitlin N., Perdomo, Germán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956289/
https://www.ncbi.nlm.nih.gov/pubmed/33668109
http://dx.doi.org/10.3390/ijms22052235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956289/
https://www.ncbi.nlm.nih.gov/pubmed/33668109
http://dx.doi.org/10.3390/ijms22052235

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