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Time-Resolved scRNA-Seq Tracks the Adaptation of a Sensitive MCL Cell Line to Ibrutinib Treatment

Since the approval of ibrutinib for relapsed/refractory mantle cell lymphoma (MCL), the treatment of this rare mature B-cell neoplasm has taken a great leap forward. Despite promising efficacy of the Bruton tyrosine kinase inhibitor, resistance arises inevitably and the underlying mechanisms remain...

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Detalles Bibliográficos
Autores principales:	Fuhr, Viktoria, Vafadarnejad, Ehsan, Dietrich, Oliver, Arampatzi, Panagiota, Riedel, Angela, Saliba, Antoine-Emmanuel, Rosenwald, Andreas, Rauert-Wunderlich, Hilka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956352/ https://www.ncbi.nlm.nih.gov/pubmed/33668876 http://dx.doi.org/10.3390/ijms22052276

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