Are In Vitro Human Blood–Brain–Tumor-Barriers Suitable Replacements for In Vivo Models of Brain Permeability for Novel Therapeutics?

SIMPLE SUMMARY: Brain cancers are a devastating disease with no cure. The aim of the study was to determine whether in vitro models can replace in vivo models to assess the brain permeability of novel drugs for brain cancer. Using the Preferred Reporting Items for Systematic Reviews and Meta-Analyse...

Descripción completa

Detalles Bibliográficos
Autores principales: Prashanth, Archana, Donaghy, Heather, Stoner, Shihani P., Hudson, Amanda L., Wheeler, Helen R., Diakos, Connie I., Howell, Viive M., Grau, Georges E., McKelvey, Kelly J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Systematic Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956470/
https://www.ncbi.nlm.nih.gov/pubmed/33668807
http://dx.doi.org/10.3390/cancers13050955

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956470/
https://www.ncbi.nlm.nih.gov/pubmed/33668807
http://dx.doi.org/10.3390/cancers13050955

Ejemplares similares