Cargando…

Phosphorylation of Phylogenetically Conserved Amino Acid Residues Confines HBx within Different Cell Compartments of Human Hepatocarcinoma Cells

Hepatitis B virus (HBV) is a circular, and partially double-stranded DNA virus. Upon infection, the viral genome is translocated into the cell nucleus, generating the covalently closed circular DNA (cccDNA) intermediate, and forming a mini chromosome. HBV HBx is a small protein displaying multiple r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Prieto, Cristian, Montecinos, Juan, Jiménez, Gustavo, Riquelme, Constanza, Garrido, Daniel, Hernández, Sergio, Loyola, Alejandra, Villanueva, Rodrigo A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956559/ https://www.ncbi.nlm.nih.gov/pubmed/33652602 http://dx.doi.org/10.3390/molecules26051254

Ejemplares similares

Canonical and Divergent N-Terminal HBx Isoform Proteins Unveiled: Characteristics and Roles during HBV Replication
por: Hernández, Sergio, et al.
Publicado: (2021)

Interferon-α sensitizes HBx-expressing hepatocarcinoma cells to chemotherapeutic drugs through inhibition of HBx-mediated NF-κB activation
por: Liu, Yanning, et al.
Publicado: (2013)

Pre- and Post-Transcriptional Control of HBV Gene Expression: The Road Traveled towards the New Paradigm of HBx, Its Isoforms, and Their Diverse Functions
por: Villanueva, Rodrigo A., et al.
Publicado: (2023)

Episomal HBV persistence within transcribed host nuclear chromatin compartments involves HBx
por: Hensel, Kai O., et al.
Publicado: (2018)

Erk phosphorylation reduces the thymoquinone toxicity in human hepatocarcinoma
por: Zhang, Bin, et al.
Publicado: (2021)

The viral transactivator HBx protein exhibits a high potential for regulation via phosphorylation through an evolutionarily conserved mechanism
por: Hernández, Sergio, et al.
Publicado: (2012)

HBX Protein-Induced Downregulation of microRNA-18a is Responsible for Upregulation of Connective Tissue Growth Factor in HBV Infection-Associated Hepatocarcinoma
por: Liu, Xiaomin, et al.
Publicado: (2016)

The enzymes LSD1 and Set1A cooperate with the viral protein HBx to establish an active hepatitis B viral chromatin state
por: Alarcon, Valentina, et al.
Publicado: (2016)

HBx-Induced NF-κB Signaling in Liver Cells Is Potentially Mediated by the Ternary Complex of HBx with p22-FLIP and NEMO
por: Lim, Keo-Heun, et al.
Publicado: (2013)

Identification of Estradiol Benzoate as an Inhibitor of HBx Using Inducible Stably Transfected HepG2 Cells Expressing HiBiT Tagged HBx
por: He, Jingjing, et al.
Publicado: (2022)

Pravastatin inhibits cell proliferation and increased MAT1A expression in hepatocarcinoma cells and in vivo models
por: Hijona, Elizabeth, et al.
Publicado: (2012)

Sodium Valproate Induces Cell Senescence in Human Hepatocarcinoma Cells
por: An, Hong-Mei, et al.
Publicado: (2013)

In Vitro Cell Density Determines the Sensitivity of Hepatocarcinoma Cells to Ascorbate
por: Fan, Hsiu-Lung, et al.
Publicado: (2022)

Endocan silencing induces programmed cell death in hepatocarcinoma
por: Yang, Jinghui, et al.
Publicado: (2017)

Farnesylthiosalicylic acid sensitizes hepatocarcinoma cells to artemisinin derivatives
por: Wu, Liping, et al.
Publicado: (2017)

Thioredoxin Downregulation Enhances Sorafenib Effects in Hepatocarcinoma Cells
por: López-Grueso, María José, et al.
Publicado: (2019)

Regulation of Multidrug Resistance Proteins by Genistein in a Hepatocarcinoma Cell Line: Impact on Sorafenib Cytotoxicity
por: Rigalli, Juan Pablo, et al.
Publicado: (2015)

Hepatitis B Virus Oncoprotein HBx Is Not an ATPase
por: Langton, Michelle, et al.
Publicado: (2020)

The Role of HBx Protein in Diseases Beyond the Liver
por: Ai, Liping, et al.
Publicado: (2023)

Effect of a New Additive Based on Textile Fibres from End-of-Life Tyres (ELT) on the Mechanical Properties of Stone Mastic Asphalt
por: Valdés-Vidal, Gonzalo, et al.
Publicado: (2023)

The Effect of miR-338-3p on HBx Deletion-Mutant (HBx-d382) Mediated Liver-Cell Proliferation through CyclinD1 Regulation
por: Fu, Xiaoyu, et al.
Publicado: (2012)

Downregulation of HBx Restrains Proliferation, Migration, and Invasion of HepG2 Cells
por: Huang, Chaoqun, et al.
Publicado: (2021)

Synthesis of magnolol and honokiol derivatives and their effect against hepatocarcinoma cells
por: Maioli, Margherita, et al.
Publicado: (2018)

Influence of oxygen partial pressure on the characteristics of human hepatocarcinoma cells
por: Trepiana, Jenifer, et al.
Publicado: (2017)

Magnetic Hyperthermia and Oxidative Damage to DNA of Human Hepatocarcinoma Cells
por: Cellai, Filippo, et al.
Publicado: (2017)

Metformin sensitises hepatocarcinoma cells to methotrexate by targeting dihydrofolate reductase
por: Wang, Yinghui, et al.
Publicado: (2021)

Regulation of the sensitivity of hepatocarcinoma cells by ORMDL3, to sorafenib by autophagy
por: Sun, Yixiao, et al.
Publicado: (2022)

Retraction: The Effect of miR-338-3p on HBx Deletion-Mutant (HBx-d382) Mediated Liver-Cell Proliferation through CyclinD1 Regulation
por: Fu, Xiaoyu, et al.
Publicado: (2013)

Nonproductive Hepatitis B Virus Covalently Closed Circular DNA Generates HBx-Related Transcripts from the HBx/Enhancer I Region and Acquires Reactivation by Superinfection in Single Cells
por: Peng, Bo, et al.
Publicado: (2022)

Genome-wide identification of direct HBx genomic targets
por: Guerrieri, Francesca, et al.
Publicado: (2017)

Relevance of HBx for Hepatitis B Virus-Associated Pathogenesis
por: Schollmeier, Anja, et al.
Publicado: (2023)

HBx sensitizes hepatocellular carcinoma cells to lapatinib by up-regulating ErbB3
por: Chen, Jhen-Yu, et al.
Publicado: (2015)

Hepatic SATB1 induces paracrine activation of hepatic stellate cells and is upregulated by HBx
por: Gong, Jin, et al.
Publicado: (2016)

Modulation of Hepatocarcinoma Cell Morphology and Activity by Parylene-C Coating on PDMS
por: Pereira-Rodrigues, Nazaré, et al.
Publicado: (2010)

Effects of STAT3 Gene Silencing and Rapamycin on Apoptosis in Hepatocarcinoma Cells
por: Zhang, Yi, et al.
Publicado: (2012)

δ-Aminolevulinic acid cytotoxic effects on human hepatocarcinoma cell lines
por: De Siervi, Adriana, et al.
Publicado: (2002)

Spheroid Formation of Hepatocarcinoma Cells in Microwells: Experiments and Monte Carlo Simulations
por: Wang, Yan, et al.
Publicado: (2016)

Metformin enhances the chemosensitivity of hepatocarcinoma cells to cisplatin through AMPK pathway
por: Dong, Hao, et al.
Publicado: (2017)

The distinct roles of mesenchymal stem cells in the initial and progressive stage of hepatocarcinoma
por: Zong, Chen, et al.
Publicado: (2018)

Exosomes released by hepatocarcinoma cells endow adipocytes with tumor-promoting properties
por: Wang, Shihua, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_8nd919e29q5uona4v1oo5tq3i3