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Whole Blood Thromboelastometry by ROTEM and Thrombin Generation by Genesia According to the Genotype and Clinical Phenotype in Congenital Fibrinogen Disorders

The outcome of congenital fibrinogen defects (CFD) is often unpredictable. Standard coagulation assays fail to predict the clinical phenotype. We aimed to assess the pheno- and genotypic associations of thrombin generation (TG) and ROTEM in CFD. We measured fibrinogen (Fg) activity and antigen, prot...

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Detalles Bibliográficos
Autores principales: Szanto, Timea, Lassila, Riitta, Lemponen, Marja, Lehtinen, Elina, Neerman-Arbez, Marguerite, Casini, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956597/
https://www.ncbi.nlm.nih.gov/pubmed/33668986
http://dx.doi.org/10.3390/ijms22052286

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