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Whole Blood Thromboelastometry by ROTEM and Thrombin Generation by Genesia According to the Genotype and Clinical Phenotype in Congenital Fibrinogen Disorders
The outcome of congenital fibrinogen defects (CFD) is often unpredictable. Standard coagulation assays fail to predict the clinical phenotype. We aimed to assess the pheno- and genotypic associations of thrombin generation (TG) and ROTEM in CFD. We measured fibrinogen (Fg) activity and antigen, prot...
Autores principales: | Szanto, Timea, Lassila, Riitta, Lemponen, Marja, Lehtinen, Elina, Neerman-Arbez, Marguerite, Casini, Alessandro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956597/ https://www.ncbi.nlm.nih.gov/pubmed/33668986 http://dx.doi.org/10.3390/ijms22052286 |
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