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Rabdosianone I, a Bitter Diterpene from an Oriental Herb, Suppresses Thymidylate Synthase Expression by Directly Binding to ANT2 and PHB2

SIMPLE SUMMARY: In the present study, we found the novel pleiotropic regulation of the oncogene product thymidylate synthase (TS) by a chemical biology approach to identify rabdosianone I-binding proteins. Rabdosianone I, which is extracted from a traditional Asian herb Isodon japonicus Hara for lon...

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Detalles Bibliográficos
Autores principales:	Watanabe, Motoki, Yamada, Yasumasa, Kurumida, Yoichi, Kameda, Tomoshi, Sukeno, Mamiko, Iizuka-Ohashi, Mahiro, Sowa, Yoshihiro, Iizumi, Yosuke, Takakura, Hideki, Miyamoto, Shingo, Sakai, Toshiyuki, Mutoh, Michihiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956614/ https://www.ncbi.nlm.nih.gov/pubmed/33652782 http://dx.doi.org/10.3390/cancers13050982

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