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Reversal of Multidrug Resistance by Apolipoprotein A1-Modified Doxorubicin Liposome for Breast Cancer Treatment
Multidrug resistance (MDR) remains a major problem in cancer therapy and is characterized by the overexpression of p-glycoprotein (P-gp) efflux pump, upregulation of anti-apoptotic proteins or downregulation of pro-apoptotic proteins. In this study, an Apolipoprotein A1 (ApoA1)-modified cationic lip...
Autores principales: | An, Duopeng, Yu, Xiaochen, Jiang, Lijing, Wang, Rui, He, Peng, Chen, Nanye, Guo, Xiaohan, Li, Xiang, Feng, Meiqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956628/ https://www.ncbi.nlm.nih.gov/pubmed/33652957 http://dx.doi.org/10.3390/molecules26051280 |
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