Synthesis of Highly Potent Anti-Inflammatory Compounds (ROS Inhibitors) from Isonicotinic Acid

In search of anti-inflammatory compounds, novel scaffolds containing isonicotinoyl motif were synthesized via an efficient strategy. The compounds were screened for their in vitro anti-inflammatory activity. Remarkably high activities were observed for isonicotinates 5–6 and 8a–8b. The compound 5 ex...

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Detalles Bibliográficos
Autores principales: Yaqoob, Sana, Nasim, Nourina, Khanam, Rahila, Wang, Yan, Jabeen, Almas, Qureshi, Urooj, Ul-Haq, Zaheer, El-Seedi, Hesham R., Jiang, Zi-Hua, Khan, Farooq-Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956706/
https://www.ncbi.nlm.nih.gov/pubmed/33652837
http://dx.doi.org/10.3390/molecules26051272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956706/
https://www.ncbi.nlm.nih.gov/pubmed/33652837
http://dx.doi.org/10.3390/molecules26051272

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