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Synthesis of Chromeno[3,4-b]piperazines by an Enol-Ugi/Reduction/Cyclization Sequence

Keto piperazines and aminocoumarins are privileged building blocks for the construction of geometrically constrained peptides and therefore valuable structures in drug discovery. Combining these two heterocycles provides unique rigid polycyclic peptidomimetics with drug-like properties including man...

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Detalles Bibliográficos
Autores principales:	Bornadiego, Ana, Neo, Ana G., Marcos, Carlos F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956738/ https://www.ncbi.nlm.nih.gov/pubmed/33673443 http://dx.doi.org/10.3390/molecules26051287

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