Cargando…
Hospitalization Costs of Lower Limb Ulcerations and Amputations in Patients with Diabetes in Romania
In this retrospective case-control study conducted in Cluj-Napoca, Romania, we assessed the effect of ulcerations/amputations on hospitalization costs of patients with diabetes. Patients with (Group 1) or without (Group 2) ulcerations/amputations (case-control ratio 3:1) admitted to a single diabete...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956777/ https://www.ncbi.nlm.nih.gov/pubmed/33668243 http://dx.doi.org/10.3390/ijerph18052230 |
_version_ | 1783664514665807872 |
---|---|
author | Sima, Diana I. Bondor, Cosmina I. Vereşiu, Ioan A. Gâvan, Norina A. Borzan, Cristina M. |
author_facet | Sima, Diana I. Bondor, Cosmina I. Vereşiu, Ioan A. Gâvan, Norina A. Borzan, Cristina M. |
author_sort | Sima, Diana I. |
collection | PubMed |
description | In this retrospective case-control study conducted in Cluj-Napoca, Romania, we assessed the effect of ulcerations/amputations on hospitalization costs of patients with diabetes. Patients with (Group 1) or without (Group 2) ulcerations/amputations (case-control ratio 3:1) admitted to a single diabetes center between 2012–2017 were included. The effects of hospitalization days, age, duration of diabetes, body mass index and glycated hemoglobin (HbA1c) on total costs was explored using a multivariate linear regression analysis, enter model. Overall, 876 patients were included (Group 1: 682, 323 [47.4%] with amputations; Group 2: 194). Median (interquartile range) total expenses in Group 1 were 40% higher compared to Group 2 (€724 [504; 1186] vs €517 [362; 645], p < 0.001). Significant differences were observed between hospitalization costs (p < 0.001), cost of food (p < 0.001), medication (p = 0.044), drugs administered at the emergency room/intensive care unit (p < 0.001) and other expenses (p = 0.003). Hospitalization costs represented 80.5% of total expenses in Group 1 and 76.3% in Group 2. In multivariate analysis, hospitalization days influenced significantly the total costs in both groups (p < 0.001); in Group 2, the effect of HbA1c was also significant (p = 0.021). Diabetic foot ulcers and subsequent amputations most likely impose a significant economic burden on the Romanian public healthcare system. |
format | Online Article Text |
id | pubmed-7956777 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-79567772021-03-16 Hospitalization Costs of Lower Limb Ulcerations and Amputations in Patients with Diabetes in Romania Sima, Diana I. Bondor, Cosmina I. Vereşiu, Ioan A. Gâvan, Norina A. Borzan, Cristina M. Int J Environ Res Public Health Article In this retrospective case-control study conducted in Cluj-Napoca, Romania, we assessed the effect of ulcerations/amputations on hospitalization costs of patients with diabetes. Patients with (Group 1) or without (Group 2) ulcerations/amputations (case-control ratio 3:1) admitted to a single diabetes center between 2012–2017 were included. The effects of hospitalization days, age, duration of diabetes, body mass index and glycated hemoglobin (HbA1c) on total costs was explored using a multivariate linear regression analysis, enter model. Overall, 876 patients were included (Group 1: 682, 323 [47.4%] with amputations; Group 2: 194). Median (interquartile range) total expenses in Group 1 were 40% higher compared to Group 2 (€724 [504; 1186] vs €517 [362; 645], p < 0.001). Significant differences were observed between hospitalization costs (p < 0.001), cost of food (p < 0.001), medication (p = 0.044), drugs administered at the emergency room/intensive care unit (p < 0.001) and other expenses (p = 0.003). Hospitalization costs represented 80.5% of total expenses in Group 1 and 76.3% in Group 2. In multivariate analysis, hospitalization days influenced significantly the total costs in both groups (p < 0.001); in Group 2, the effect of HbA1c was also significant (p = 0.021). Diabetic foot ulcers and subsequent amputations most likely impose a significant economic burden on the Romanian public healthcare system. MDPI 2021-02-24 2021-03 /pmc/articles/PMC7956777/ /pubmed/33668243 http://dx.doi.org/10.3390/ijerph18052230 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Sima, Diana I. Bondor, Cosmina I. Vereşiu, Ioan A. Gâvan, Norina A. Borzan, Cristina M. Hospitalization Costs of Lower Limb Ulcerations and Amputations in Patients with Diabetes in Romania |
title | Hospitalization Costs of Lower Limb Ulcerations and Amputations in Patients with Diabetes in Romania |
title_full | Hospitalization Costs of Lower Limb Ulcerations and Amputations in Patients with Diabetes in Romania |
title_fullStr | Hospitalization Costs of Lower Limb Ulcerations and Amputations in Patients with Diabetes in Romania |
title_full_unstemmed | Hospitalization Costs of Lower Limb Ulcerations and Amputations in Patients with Diabetes in Romania |
title_short | Hospitalization Costs of Lower Limb Ulcerations and Amputations in Patients with Diabetes in Romania |
title_sort | hospitalization costs of lower limb ulcerations and amputations in patients with diabetes in romania |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956777/ https://www.ncbi.nlm.nih.gov/pubmed/33668243 http://dx.doi.org/10.3390/ijerph18052230 |
work_keys_str_mv | AT simadianai hospitalizationcostsoflowerlimbulcerationsandamputationsinpatientswithdiabetesinromania AT bondorcosminai hospitalizationcostsoflowerlimbulcerationsandamputationsinpatientswithdiabetesinromania AT veresiuioana hospitalizationcostsoflowerlimbulcerationsandamputationsinpatientswithdiabetesinromania AT gavannorinaa hospitalizationcostsoflowerlimbulcerationsandamputationsinpatientswithdiabetesinromania AT borzancristinam hospitalizationcostsoflowerlimbulcerationsandamputationsinpatientswithdiabetesinromania |