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Reversal of the Inflammatory Responses in Fabry Patient iPSC-Derived Cardiovascular Endothelial Cells by CRISPR/Cas9-Corrected Mutation

The late-onset type of Fabry disease (FD) with GLA IVS4 + 919G > A mutation has been shown to lead to cardiovascular dysfunctions. In order to eliminate variations in other aspects of the genetic background, we established the isogenic control of induced pluripotent stem cells (iPSCs) for the ide...

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Detalles Bibliográficos
Autores principales:	Song, Hui-Yung, Yang, Yi-Ping, Chien, Yueh, Lai, Wei-Yi, Lin, Yi-Ying, Chou, Shih-Jie, Wang, Mong-Lien, Wang, Chien-Ying, Leu, Hsin-Bang, Yu, Wen-Chung, Chien, Chian-Shiu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956852/ https://www.ncbi.nlm.nih.gov/pubmed/33673551 http://dx.doi.org/10.3390/ijms22052381

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