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Exosome miR-501-3p Elevation Contributes to Progression of Vascular Stiffness
Background: Tight junction (TJ) disruption and dysfunction are involved in the progression of arteriosclerosis. miR-501-3p regulates endothelial TJ protein-1, resulting in TJ disruption. Because exosomal microRNAs can travel to distant tissues and influence cell behavior, patients with elevated miR-...
Autores principales: | Toyama, Kensuke, Igase, Michiya, Spin, Joshua M., Abe, Yasunori, Javkhlant, Amarsanaa, Okada, Yoko, Wagenhäuser, Markus U., Schelzig, Hubert, Tsao, Philip S., Mogi, Masaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Circulation Society
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7956882/ https://www.ncbi.nlm.nih.gov/pubmed/33738350 http://dx.doi.org/10.1253/circrep.CR-20-0135 |
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